Gene: C1orf56
Official Full Name: chromosome 1 open reading frame 56provided by HGNC
Gene Summary: This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19325 | C1orf56 Knockout cell line (HeLa) | Human | C1orf56 | 1:3~1:6 | Negative | Online Inquiry |
KO19326 | C1orf56 Knockout cell line (HEK293) | Human | C1orf56 | 1:3~1:6 | Negative | Online Inquiry |
KO19327 | C1orf56 Knockout cell line (A549) | Human | C1orf56 | 1:3~1:4 | Negative | Online Inquiry |
C1orf56 Gene Knockout Cell Lines are laboratory-engineered cellular models designed to specifically disrupt the function of the C1orf56 gene, which has been implicated in various biological pathways and diseases. This knockout feature allows researchers to investigate the precise role of C1orf56 in cellular processes, including its potential contribution to disease pathology. By utilizing CRISPR-Cas9 or similar genome-editing technologies, these cell lines provide a robust platform for genetic analysis.
The primary function of C1orf56 Gene Knockout Cell Lines is to enable the study of gene function, pathway elucidation, and phenotypic characterization at a cellular level. Researchers can perform comparative analyses between knockout and wild-type cell lines to assess the consequent biological effects of gene loss. The mechanistic insights gained from these studies are crucial for understanding the role of C1orf56 in activities such as cell proliferation, differentiation, and response to stress, which may be linked to disorders ranging from cancer to neurodegenerative diseases.
In research and clinical settings, C1orf56 Gene Knockout Cell Lines hold significant importance due to their potential applications in drug discovery and therapeutic development. By elucidating the biological mechanisms underlying C1orf56 function, these cell lines can aid in identifying new targets for pharmacological intervention or uncovering novel biomarkers for disease diagnosis and prognosis.
Distinct advantages of utilizing our C1orf56 Gene Knockout Cell Lines include their high specificity and reproducibility, supported by thorough quality control and assurance protocols. Researchers benefit from a ready-to-use model that minimizes the time and cost typically associated with generating custom knockout lines. Furthermore, our cell lines are generated from multiple relevant backgrounds, increasing their applicability across diverse experimental conditions.
The value of C1orf56 Gene Knockout Cell Lines lies in their ability to provide critical insights into gene function that directly impact translational research efforts. These are essential tools for researchers and clinicians who aim to advance both basic science and therapeutic strategies.
With years of experience in developing high-quality biological products, our company is committed to delivering innovative solutions that empower researchers and pave the way for breakthroughs in genetic research and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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