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C1QBP Knockout Cell Lines

Gene: C1QBP

Official Full Name: complement C1q binding proteinprovided by HGNC

Gene Summary: The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00306 C1QBP Knockout cell line (HeLa) Human C1QBP 1:3~1:6 Negative Online Inquiry
KO07066 C1QBP Knockout cell line (HCT 116) Human C1QBP 1:2~1:4 Negative Online Inquiry
KO07067 C1QBP Knockout cell line (HEK293) Human C1QBP 1:3~1:6 Negative Online Inquiry
KO07068 C1QBP Knockout cell line (A549) Human C1QBP 1:3~1:4 Negative Online Inquiry

Background

C1QBP Gene Knockout Cell Lines represent a pivotal tool for researchers seeking to elucidate the biological functions of the C1QBP gene, known for its involvement in diverse cellular processes, including complement system regulation, cell adhesion, and apoptosis. These genetically modified cell lines are produced through advanced CRISPR/Cas9 technology, which enables precise editing of the C1QBP gene, effectively rendering it non-functional. This knockout allows for the systematic study of the consequences of C1QBP loss in cellular functions, providing invaluable insight into its role in various physiological and pathological contexts.

The primary function of the C1QBP gene is to code for a protein that plays a critical role in the innate immune response. By utilizing C1QBP Gene Knockout Cell Lines, researchers can investigate its mechanistic pathways, including interactions with other complement components and its effects on inflammation and immune modulation. Such investigations are crucial for understanding diseases in which C1QBP is implicated, such as autoimmune disorders, cancers, and infectious diseases.

One of the significant advantages of these knockout cell lines over other experimental models lies in their ability to provide a more precise and specific evaluation of gene function without the confounding effects often associated with whole-animal models. Additionally, they enable high-throughput screening of potential therapeutic compounds targeting pathways regulated by C1QBP, making them particularly valuable in drug discovery.

For researchers and clinicians, the C1QBP Gene Knockout Cell Lines facilitate a deeper understanding of pathophysiological mechanisms, thereby enhancing the potential for developing targeted therapies. Their capacity for reproducibility and scalability ensures that researchers can conduct systematic studies with reliable datasets, reinforcing the significance of this product in advancing scientific knowledge.

Our company specializes in providing high-quality biological research tools backed by extensive expertise in genetic engineering and cell line development. This commitment to excellence ensures that researchers can count on our products to drive innovation and discovery in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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