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BORCS5 Knockout Cell Lines

Gene: BORCS5

Official Full Name: BLOC-1 related complex subunit 5provided by HGNC

Gene Summary: Involved in lysosome localization and organelle transport along microtubule. Located in cytoplasmic side of lysosomal membrane; plasma membrane; and plus-end kinesin complex. Part of BORC complex. Implicated in colorectal adenocarcinoma. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30416 BORCS5 Knockout cell line (HeLa) Human BORCS5 1:3~1:6 Negative Online Inquiry
KO30417 BORCS5 Knockout cell line (HCT 116) Human BORCS5 1:2~1:4 Negative Online Inquiry
KO30418 BORCS5 Knockout cell line (HEK293) Human BORCS5 1:3~1:6 Negative Online Inquiry
KO30419 BORCS5 Knockout cell line (A549) Human BORCS5 1:3~1:4 Negative Online Inquiry

Background

BORCS5 Gene Knockout Cell Lines are specialized cell lines that have undergone targeted genetic modification to disrupt the BORCS5 gene. This gene is essential in the context of cellular signaling and endosomal trafficking, playing a pivotal role in maintaining cellular integrity and functions. The knockout of this gene allows researchers to effectively study its impact on various cellular processes, including vesicular transport and cellular response to stresses.

The key mechanism of action lies in the precise gene-editing techniques employed, such as CRISPR-Cas9, which enables the specific disruption of the BORCS5 gene. By analyzing these modified cell lines, researchers can gain insights into the downstream effects of BORCS5 knockout. This can lead to a deeper understanding of its role in diseases, particularly in neurodegenerative conditions and cancer, where cellular trafficking plays a crucial role in pathology.

The scientific importance of BORCS5 Gene Knockout Cell Lines is substantial, as they provide a unique tool for investigating gene function in both basic research and clinical settings. They are instrumental in elucidating the pathological mechanisms underlying diseases and can facilitate the development of potential therapeutic strategies. Their application extends to drug discovery and development, where understanding gene function can guide the design of novel interventions.

One significant advantage of our BORCS5 Gene Knockout Cell Lines is their reliability and reproducibility, traits that are paramount in scientific research. Unlike traditional cell lines, these knockout models provide a clearer understanding of the gene's specific role by eliminating confounding variables associated with gene expression. Additionally, our extensive quality control measures ensure that each cell line meets stringent scientific standards.

For researchers and clinicians, the ability to study the BORCS5 gene in a knockout model provides essential data that can drive further innovation in understanding and treating related diseases. Our commitment to quality and scientific rigor positions our BORCS5 Gene Knockout Cell Lines as an invaluable resource in modern biological research.

Our company is dedicated to advancing research through innovative biological products, and we pride ourselves on our expertise in genetic modification technologies, providing products that empower scientists and researchers to unlock new insights in cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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