Home / B3GALNT2 Knockout Cell Lines

B3GALNT2 Knockout Cell Lines

Gene: B3GALNT2

Official Full Name: beta-1,3-N-acetylgalactosaminyltransferase 2provided by HGNC

Gene Summary: This gene encodes a member of the glycosyltransferase 31 family. The encoded protein synthesizes GalNAc:beta-1,3GlcNAc, a novel carbohydrate structure, on N- and O-glycans. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2013]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23259 B3GALNT2 Knockout cell line (HeLa) Human B3GALNT2 1:3~1:6 Negative Online Inquiry
KO23260 B3GALNT2 Knockout cell line (HCT 116) Human B3GALNT2 1:2~1:4 Negative Online Inquiry
KO23261 B3GALNT2 Knockout cell line (HEK293) Human B3GALNT2 1:3~1:6 Negative Online Inquiry
KO23262 B3GALNT2 Knockout cell line (A549) Human B3GALNT2 1:3~1:4 Negative Online Inquiry

Background

B3GALNT2 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to inactivate the B3GALNT2 gene, which plays a crucial role in glycosylation processes. These genetically modified cell lines are essential tools for studying the biological functions of the B3GALNT2 protein and its implications in various physiological and pathological conditions, including cancer and inflammatory responses.

The primary function of the B3GALNT2 gene is to encode a glycosyltransferase involved in the synthesis of specific glycan structures, which are pivotal for cell signaling, immune response, and cell-cell interactions. By creating knockout cell lines, researchers can elucidate the gene’s role in these processes and investigate how its absence affects cell behavior, signaling pathways, and overall cellular health. The mechanistic insights gained from these models can contribute to a better understanding of diseases where glycosylation patterns are disrupted.

In research and clinical settings, the B3GALNT2 knockout cell lines are indispensable for drug discovery and development, as they allow scientists to screen therapeutic compounds targeting glycosylation pathways. Furthermore, these cell lines are valuable for elucidating the molecular basis of glyco-related diseases, providing a platform for validating potential biomarkers for diagnostics or therapeutic targets.

What sets B3GALNT2 Gene Knockout Cell Lines apart from alternative methods, such as transient transfection or RNA interference, is their stable and consistent genetic modification. This stability allows for reproducible experiments over time, ensuring that researchers can rely on the accuracy of their findings. Additionally, these cell lines streamline the workflow in laboratories, eliminating the need for repeated transfection procedures.

For researchers and clinicians, the value of B3GALNT2 Gene Knockout Cell Lines lies in their ability to provide insights into complex biological mechanisms with precision and reliability. With our extensive expertise in genetic engineering and cell line development, our company is committed to offering high-quality biological products that advance scientific research and lead to innovative breakthroughs in medicine.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.