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ATP10D Knockout Cell Lines

Gene: ATP10D

Official Full Name: ATPase phospholipid transporting 10D (putative)provided by HGNC

Gene Summary: Enables glycosylceramide flippase activity. Predicted to be involved in phospholipid translocation. Located in endoplasmic reticulum; nucleoplasm; and plasma membrane. Part of phospholipid-translocating ATPase complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19561 ATP10D Knockout cell line (HeLa) Human ATP10D 1:3~1:6 Negative Online Inquiry
KO19562 ATP10D Knockout cell line (HCT 116) Human ATP10D 1:2~1:4 Negative Online Inquiry
KO19563 ATP10D Knockout cell line (HEK293) Human ATP10D 1:3~1:6 Negative Online Inquiry
KO19564 ATP10D Knockout cell line (A549) Human ATP10D 1:3~1:4 Negative Online Inquiry

Background

ATP10D Gene Knockout Cell Lines are genetically modified cell lines that have been specifically engineered to disrupt the ATP10D gene, which encodes a member of the P-type ATPase family responsible for the transport of various metal ions across the cell membrane. This product provides a powerful tool for research into the physiological and pathological roles of ATP10D, particularly in mechanisms of cellular ion transport and homeostasis. By knocking out ATP10D, researchers can study the functional consequences of the gene's loss, such as alterations in cellular signaling pathways, changes in ion balance, and other metabolic effects that may not be observable in wild-type cells.

The key functions of ATP10D Gene Knockout Cell Lines lie in their ability to facilitate investigations into disease models, specifically those related to ion dysregulation such as neurodegenerative disorders and certain cancers. The knockout mechanism allows scientists to explore the impact of ATP10D deficiency on cellular behaviors, and evaluate therapeutic strategies aimed at restoring normal ion homeostasis or compensating for the loss of ATP10D function.

The scientific importance of these knockout cell lines extends to various applications, including drug screening, functional genomics, and biomarker discovery. In clinical settings, understanding the role of ATP10D may provide insights into treatment modalities for conditions influenced by ion transport disturbances.

Compared to alternative products, ATP10D Gene Knockout Cell Lines offer precision and specificity, as they have been developed using advanced CRISPR/Cas9 technologies, ensuring a clean knockout without off-target effects. This advantage leads to more reliable and reproducible results in experiments. Furthermore, they are readily available for researchers looking to expedite their work without the extensive time and resources typically required to develop knockout models from scratch.

This product represents a significant advancement for biologists and clinicians who aim to elucidate the complex roles of ion transporters in health and disease. Our commitment to high-quality, reliable genetic tools is underscored by our team's experience in molecular genetics and cell biology, ensuring that users of ATP10D Gene Knockout Cell Lines can confidently pursue their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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