Gene: ATAD1
Official Full Name: ATPase family AAA domain containing 1provided by HGNC
Gene Summary: Predicted to enable ATP hydrolysis activity. Involved in extraction of mislocalized protein from mitochondrial outer membrane. Located in mitochondrial outer membrane and peroxisomal membrane. Implicated in hyperekplexia 4. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24539 | ATAD1 Knockout cell line (HeLa) | Human | ATAD1 | 1:3~1:6 | Negative | Online Inquiry |
KO24540 | ATAD1 Knockout cell line (HCT 116) | Human | ATAD1 | 1:2~1:4 | Negative | Online Inquiry |
KO24541 | ATAD1 Knockout cell line (HEK293) | Human | ATAD1 | 1:3~1:6 | Negative | Online Inquiry |
KO24542 | ATAD1 Knockout cell line (A549) | Human | ATAD1 | 1:3~1:4 | Negative | Online Inquiry |
ATAD1 Gene Knockout Cell Lines are genetically modified cell lines in which the ATAD1 gene has been inactivated or “knocked out,” allowing researchers to study the effects and functions of this particular gene more comprehensively. ATAD1 encodes an ATPase that has been implicated in various cellular processes, including mitochondrial dynamics and protein homeostasis. By creating knockout models, scientists can elucidate the biological role of ATAD1, examine the associated pathways, and determine how its absence impacts cellular physiology.
The primary mechanism of these knockout cell lines involves the use of CRISPR/Cas9 technology or similar genome editing techniques to induce precise mutations within the ATAD1 gene. This technique ensures a high fidelity in gene editing, resulting in a complete loss of function of the ATAD1 protein. Such models are pivotal for investigating the gene's contribution to mitochondrial dysfunction, neurodegenerative disorders, and other pathophysiological conditions.
In research and clinical settings, ATAD1 Gene Knockout Cell Lines hold significant importance, particularly for studies related to cellular metabolism and the underlying causes of diseases linked to mitochondrial dysfunction. They provide a unique platform for drug discovery, therapeutic target validation, and the understanding of disease mechanisms. Their precise editing provides researchers with tools to generate reproducible results that might elucidate potential biomarker candidates or therapeutic interventions.
Compared to traditional gene knockout techniques, these cell lines offer several advantages, including improved specificity, reduced off-target effects, and the ability to generate stable cell populations with consistent genetic backgrounds. This level of precision is crucial for studies focused on gene function and interaction, making these cell lines indispensable for researchers seeking reliable, reproducible results.
For researchers and clinicians, the value of ATAD1 Gene Knockout Cell Lines lies in their ability to drive innovative scientific inquiry and therapeutic strategies. With the ongoing demand for advanced research models in molecular biology and genetics, this product provides an essential resource for pioneering studies in gene function, cell signaling, and disease mechanisms.
Our company specializes in providing high-quality, genetically engineered cell lines tailored to meet the diverse needs of the scientific community. With a commitment to excellence and innovation, we enable researchers to explore the complexities of biology with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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