Home / ASTE1 Knockout Cell Lines

ASTE1 Knockout Cell Lines

Gene: ASTE1

Official Full Name: asteroid homolog 1provided by HGNC

Gene Summary: Enables 3' overhang single-stranded DNA endodeoxyribonuclease activity. Involved in double-strand break repair via homologous recombination and double-strand break repair via nonhomologous end joining. Implicated in Lynch syndrome and mismatch repair cancer syndrome. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27238 ASTE1 Knockout cell line (HeLa) Human ASTE1 1:3~1:6 Negative Online Inquiry
KO27239 ASTE1 Knockout cell line (HCT 116) Human ASTE1 1:2~1:4 Negative Online Inquiry
KO27240 ASTE1 Knockout cell line (HEK293) Human ASTE1 1:3~1:6 Negative Online Inquiry
KO27241 ASTE1 Knockout cell line (A549) Human ASTE1 1:3~1:4 Negative Online Inquiry

Background

ASTE1 Gene Knockout Cell Lines are precisely engineered cellular models designed to study the function of the ASTE1 gene, which plays a crucial role in various cellular processes, including mitochondrial dynamics and stress responses. These knockout cell lines are developed using advanced CRISPR-Cas9 gene editing technology, resulting in stable modifications that completely abrogate ASTE1 expression. By utilizing these cell lines, researchers can dissect the biological pathways regulated by this gene and investigate its implications in disease mechanisms.

The primary function of the ASTE1 Gene Knockout Cell Lines lies in their ability to provide insights into the gene's role in cellular metabolism, apoptosis, and cancer progression. By comparing the knockout lines to their parental counterparts, scientists can elucidate how the absence of ASTE1 affects cellular physiology and responses to external stimuli. This can lead to a better understanding of various conditions associated with mitochondrial dysfunction or other pathologies related to oxidative stress.

In the realm of scientific research and clinical applications, these knockout cell lines serve as invaluable tools. They are instrumental in drug discovery, allowing researchers to identify potential therapeutic targets and validate the efficacy of novel compounds. Furthermore, by studying the phenotypic changes exhibited by these cells, researchers can gain critical insight into potential biomarkers for disease progression or treatment response.

What sets ASTE1 Gene Knockout Cell Lines apart from alternative products is their stringent validation process and the precision of the knockout construct. Each line undergoes extensive characterization to ensure the quality and reproducibility of results, thus providing researchers with reliable data for their projects. Moreover, the user-friendly format and comprehensive support provided make it easier for clients to incorporate these models into their existing research frameworks.

For researchers, clinicians, and biotech professionals, leveraging ASTE1 Gene Knockout Cell Lines means advancing their understanding of fundamental biological processes and enhancing the translational potential of their findings. Our company's expertise in cellular model development is rooted in cutting-edge techniques and a commitment to providing high-quality biological products that meet the rigorous demands of modern science, making us a trusted partner in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.