Gene: ARMC3
Official Full Name: armadillo repeat containing 3provided by HGNC
Gene Summary: Armadillo/beta-catenin (CTNNB1; MIM 116806)-like (ARM) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis (Li et al., 2006 [PubMed 16915934]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28712 | ARMC3 Knockout cell line (HCT 116) | Human | ARMC3 | 1:2~1:4 | Negative | Online Inquiry |
ARMC3 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the ARMC3 gene, which encodes for the Armadillo repeat containing 3 protein—an important regulator in various cellular pathways, including cell adhesion, structure, and signal transduction mechanisms. These knockout cell lines are generated using cutting-edge CRISPR/Cas9 technology, allowing for precise and efficient disruption of the gene, making them invaluable tools for dissecting the biological roles of ARMC3 in cancer biology, developmental studies, and other cellular processes.
The primary function of the ARMC3 Gene Knockout Cell Lines is to facilitate in-depth analysis of the loss-of-function effects attributed to ARMC3. Researchers can employ these models to study alterations in cell proliferation, migration, and invasion, providing insight into the underlying mechanisms by which ARMC3 contributes to disease states. The ability to closely observe these cellular changes in a controlled environment greatly enhances our understanding of the gene's role in relevant biological processes.
Due to their specificity and relevance, these cell lines hold significant scientific importance in both basic and applied research. They can serve in drug discovery efforts, allowing researchers to evaluate the efficacy of therapeutic compounds targeting ARMC3-related pathways, as well as in translational studies aimed at potential clinical applications.
What sets our ARMC3 Gene Knockout Cell Lines apart from other alternatives is their high fidelity and reproducibility, bolstered by our rigorous quality control processes. Each cell line is thoroughly characterized to ensure consistent performance, offering researchers confidence in their experimental outcomes. Additionally, the capability to revert the knockout with precise CRISPR technologies allows for versatile experimental design, further enhancing usability.
This product is indispensable for researchers and clinicians striving to advance the understanding of ARMC3's functions and its implications in health and disease. By utilizing our ARMC3 Gene Knockout Cell Lines, users are not only gaining a valuable research tool but also tapping into our company’s extensive expertise in genetic manipulation and cellular biology. We are committed to delivering high-quality biological products that empower scientific innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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