Gene: ARL14
Official Full Name: ARF like GTPase 14provided by HGNC
Gene Summary: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26224 | ARL14 Knockout cell line (A549) | Human | ARL14 | 1:3~1:4 | Negative | Online Inquiry |
ARL14 Gene Knockout Cell Lines are genetically engineered cell lines that enable the study of the ARL14 gene's functional role in various physiological and pathological contexts. By employing CRISPR-Cas9 gene-editing technology, these cell lines have been specifically designed to disrupt the expression of the ARL14 gene, which encodes a small GTPase involved in intracellular signaling pathways. This knockout allows for the detailed investigation of ARL14's involvement in processes such as cell migration, differentiation, and the modulation of neuronal activity, providing invaluable insights into its implications in diseases like cancer and neurological disorders.
The primary mechanism of action relies on the introduced mutations in the ARL14 gene, preventing the synthesis of the protein and enabling researchers to observe the resultant phenotypic changes. These alterations facilitate a deeper understanding of the gene's biological roles through comparative studies with wild-type cell lines. The scientific importance of ARL14 Gene Knockout Cell Lines lies in their ability to serve as a versatile tool in both basic and applied research, allowing scientists to dissect the pathways and interactions governed by this small GTPase.
What sets our ARL14 Gene Knockout Cell Lines apart from competing products is not only their validated knockout efficiency but also their stringent quality control processes, ensuring reproducibility and reliability in experimental results. Additionally, they are provided with comprehensive documentation and support, including protocols for experimental use, which streamline the research process.
For researchers and clinicians, the value of ARL14 Gene Knockout Cell Lines lies in their potential to accelerate discoveries related to gene function and disease mechanisms, ultimately contributing to the development of targeted therapies. With a commitment to advancing scientific inquiry, our company specializes in developing high-quality genetic tools that empower researchers to push the boundaries of knowledge in molecular biology, genetics, and cell biology.
Please note that all services are for research use only. Not intended for any clinical use.
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