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ANOS1 Knockout Cell Lines

Gene: ANOS1

Official Full Name: anosmin 1provided by HGNC

Gene Summary: Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37000 ANOS1 Knockout cell line (HeLa) Human ANOS1 1:3~1:6 Negative Online Inquiry
KO37001 ANOS1 Knockout cell line (HEK293) Human ANOS1 1:3~1:6 Negative Online Inquiry

Background

ANOS1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to inactivate the ANOS1 gene, which plays a critical role in the development of the olfactory system and, consequently, in the perception of smell. By employing the CRISPR-Cas9 gene-editing technology, these cell lines allow for precise genomic modifications that facilitate the study of gene function and the underlying mechanisms of diseases related to anosmia and other olfactory system disorders.

The key functionality of the ANOS1 Gene Knockout Cell Lines lies in their ability to simulate the effects of ANOS1 loss-of-function mutations in a controlled laboratory environment. This not only aids researchers in elucidating the pathways influenced by ANOS1 but also enables the investigation of compensatory mechanisms that cells may employ in its absence. The application of these cell lines spans both basic and applied research, including drug development and gene therapy approaches targeting olfactory and neurodevelopmental disorders, thus proving to be invaluable to both academic laboratories and clinical research institutions.

What sets our ANOS1 Gene Knockout Cell Lines apart from competing products is their high-quality validation, characterized by exceptional gene edit efficiency and phenotypic consistency across multiple passages. This reliability reduces variability in experiments, leading to more reproducible results. Additionally, our comprehensive technical support and robust documentation provide users with the necessary resources to quickly integrate these models into their research workflows.

Given the increasing attention to the link between genetic mutations and sensory disorders, ANOS1 Gene Knockout Cell Lines offer an unprecedented opportunity to deepen understanding of anosmia, paving the way for novel therapeutic strategies. As a leader in the field of biological products, our company is committed to supporting the scientific community with innovative and reliable tools that drive discovery and foster advancements in health and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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