Gene: ALX1
Official Full Name: ALX homeobox 1provided by HGNC
Gene Summary: The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34313 | ALX1 Knockout cell line (HeLa) | Human | ALX1 | 1:3~1:6 | Negative | Online Inquiry |
KO34314 | ALX1 Knockout cell line (HEK293) | Human | ALX1 | 1:3~1:6 | Negative | Online Inquiry |
KO34315 | ALX1 Knockout cell line (A549) | Human | ALX1 | 1:3~1:4 | Negative | Online Inquiry |
ALX1 Gene Knockout Cell Lines are specialized cellular models developed to investigate the physiological and pathological roles of the ALX1 gene, known for its involvement in various biological processes, including cell signaling, development, and non-coding RNA regulation. These genetically modified cell lines are created using sophisticated CRISPR/Cas9 gene-editing techniques, which allow for the precise knockout of ALX1, leading to a complete loss of function and enabling researchers to study the resultant molecular and phenotypic changes.
The primary function of these cell lines is to facilitate a better understanding of the ALX1 gene's contribution to cellular processes. By providing a controlled environment where the gene is absent, researchers can elucidate pathways affected by ALX1 and identify its role in disease mechanisms, such as cancer and autoimmune disorders. The knockout cell lines are invaluable tools in basic and translational research, offering insights that may lead to novel therapeutic strategies.
A standout feature of ALX1 Gene Knockout Cell Lines is their versatility in applications, ranging from drug discovery to functional genomics. Compared to traditional methods of gene silencing, such as RNA interference, the knockout approach offers a more stable and permanent alteration, ensuring that experimental observations are robust and reproducible. This genetic precision allows for the thorough exploration of gene-dependant phenotypes and serves as a superior alternative to existing models, which may have off-target effects.
Researchers and clinicians benefit significantly from utilizing these knockout cell lines, as they streamline experimental workflows and promote greater clarity in data interpretation. The ability to manipulate a single gene opens avenues for targeted studies that can address specific biological questions, making findings more impactful.
Our company prides itself on delivering high-quality biological products, underpinned by our commitment to scientific advancement and collaboration. By harnessing cutting-edge genetic engineering technologies, we provide exceptional tools for researchers striving to advance their understanding of gene function and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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