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ADM Knockout Cell Lines

Gene: ADM

Official Full Name: adrenomedullinprovided by HGNC

Gene Summary: The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO39088 ADM Knockout cell line (HeLa) Human ADM 1:3~1:6 Negative Online Inquiry
KO39089 ADM Knockout cell line (HCT 116) Human ADM 1:2~1:4 Negative Online Inquiry
KO39090 ADM Knockout cell line (HEK293) Human ADM 1:3~1:6 Negative Online Inquiry
KO39091 ADM Knockout cell line (A549) Human ADM 1:3~1:4 Negative Online Inquiry

Background

ADM Gene Knockout Cell Lines are advanced biological research tools that facilitate the study of gene function by providing cell lines in which specific genes have been selectively disrupted or eliminated. The mechanism underlying these knockout models involves the utilization of CRISPR-Cas9 or other gene-editing technologies, allowing precise modifications to the genome. This targeted approach enables researchers to investigate the phenotypic consequences of gene loss, elucidate pathways, and explore potential therapeutic targets with enhanced accuracy and reproducibility.

The scientific importance of ADM Gene Knockout Cell Lines lies in their broad applications across various fields, including genetics, cancer research, and drug discovery. By enabling the exploration of gene function in a controlled environment, these cell lines can significantly accelerate the development of novel therapeutics and provide insights into disease mechanisms. Furthermore, their utility extends to personalized medicine, where understanding specific genetic alterations within patients can inform tailored treatment strategies.

Compared to traditional cell lines, ADM Gene Knockout Cell Lines offer distinct advantages. They save time and resources by providing pre-validated models, reduce variability associated with genetic background differences, and allow for high-throughput screening applications. Their ease of use in various experimental setups positions them as an invaluable resource for both academic and pharmaceutical research environments.

For researchers and clinicians, investing in ADM Gene Knockout Cell Lines means accessing a powerful tool that enhances experimental design, improves data reliability, and ultimately contributes to faster scientific breakthroughs. Our company's commitment to excellence in biological products ensures that these knockout models are rigorously validated and supported by a team of experts dedicated to advancing scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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