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ADGRG5 Knockout Cell Lines

Gene: ADGRG5

Official Full Name: adhesion G protein-coupled receptor G5provided by HGNC

Gene Summary: This gene encodes a member of the adhesion family of G-protein coupled receptors. Members of this family are characterized by long N-termini and multiple functional domains. They may play a role in the immune system as well as in the central nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27532 ADGRG5 Knockout cell line (HCT 116) Human ADGRG5 1:2~1:4 Negative Online Inquiry

Background

ADGRG5 Gene Knockout Cell Lines represent a sophisticated tool for the study of the adhesion G protein-coupled receptor family, particularly the role of ADGRG5 in various physiological and pathological processes. These cell lines are engineered to have a precise knockout of the ADGRG5 gene, allowing researchers to investigate the biological functions and signaling pathways associated with this receptor without the confounding variables introduced by its expression.

The primary mechanism underlying the utility of these knockout cell lines is their ability to provide a controlled environment where the absence of ADGRG5 can be observed and analyzed. This knockout enables researchers to discern the receptor's role in cellular processes such as migration, proliferation, and response to stimuli, as well as its potential implications in diseases like cancer or metabolic disorders. By examining these functions without the influence of ADGRG5, scientists can draw clearer connections between receptor activity and cellular outcomes.

In the scientific community, ADGRG5 Gene Knockout Cell Lines hold significant importance as they facilitate both basic and applied research efforts. Their applications extend across various fields, including cancer biology, pharmacology, and developmental biology, making them essential for researchers aiming to publish impactful findings that can lead to novel therapeutic strategies.

Compared to alternative models, such as wild-type or overexpressing cell lines, the knockout approach provides a distinct advantage by eliminating background interference from normal receptor activities, thus enhancing the accuracy of experimental outcomes. These cell lines enable a more straightforward investigation into the specific functions of ADGRG5, making them a preferred choice for precise experimental designs.

For researchers and clinicians, the ADGRG5 Gene Knockout Cell Lines offer unparalleled value by empowering studies that aim to uncover the intricacies of GPCR signaling and its implications in health and disease. These insights are critical for developing innovative treatments and advancing scientific understanding within this dynamic field.

Our company prides itself on delivering high-quality genetic models and tools for cutting-edge research. With a commitment to scientific excellence, we support researchers in their quest to unlock the mysteries of cellular signaling and contribute to advancements in medical science.

Please note that all services are for research use only. Not intended for any clinical use.

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