Gene: ADAP1
Official Full Name: ArfGAP with dual PH domains 1provided by HGNC
Gene Summary: Enables GTPase activator activity. Predicted to be involved in cell surface receptor signaling pathway. Located in cytosol; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31295 | ADAP1 Knockout cell line (HeLa) | Human | ADAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO31296 | ADAP1 Knockout cell line (HCT 116) | Human | ADAP1 | 1:2~1:4 | Negative | Online Inquiry |
KO31297 | ADAP1 Knockout cell line (HEK293) | Human | ADAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO31298 | ADAP1 Knockout cell line (A549) | Human | ADAP1 | 1:3~1:4 | Negative | Online Inquiry |
ADAP1 Gene Knockout Cell Lines represent a pivotal advancement in the field of genetic research, specifically designed for the study of the ADAP1 gene, known for its role in immune cell signaling and cytoskeletal dynamics. These cell lines have been precisely engineered to eliminate the expression of the ADAP1 gene through CRISPR-Cas9 technology, allowing researchers to investigate the consequences of its absence on cellular behavior and immune responses.
The major function of ADAP1 involves the regulation of T-cell receptor signaling and the modulation of integrin activation, critical processes for proper immune system functioning. By utilizing these knockout cell lines, scientists can elucidate the intricate pathways that govern immune tolerance and autoimmunity, providing insights into diseases that arise from malfunctions in these mechanisms.
The scientific importance of ADAP1 Gene Knockout Cell Lines is multifaceted. In clinical research, they serve as invaluable tools in the development of therapeutic strategies targeting lymphocyte activation, potentially revolutionizing treatments for autoimmune diseases and cancers. Moreover, their application in drug discovery enables high-throughput screening of compounds that could restore normal immune function or inhibit aberrant signaling pathways.
What sets ADAP1 Gene Knockout Cell Lines apart from alternative models is their high fidelity and reproducibility, ensured by rigorous quality controls during the knockout process. These cell lines are also compatible with a variety of assays, including flow cytometry and functional assays, enhancing their utility across multiple research paradigms.
For researchers and clinicians seeking reliable, cutting-edge tools to explore the complexities of the immune system, ADAP1 Gene Knockout Cell Lines offer a unique asset that complements both basic and translational research. Our company is dedicated to providing high-quality biological products backed by extensive expertise, ensuring that every product meets rigorous scientific standards to facilitate breakthrough discoveries in the field.
Please note that all services are for research use only. Not intended for any clinical use.
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