Gene: ACOXL
Official Full Name: acyl-CoA oxidase likeprovided by HGNC
Gene Summary: Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA oxidase. Predicted to be located in peroxisomal matrix. Predicted to be active in peroxisome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20044 | ACOXL Knockout cell line (HCT 116) | Human | ACOXL | 1:2~1:4 | Negative | Online Inquiry |
KO20045 | ACOXL Knockout cell line (HEK293) | Human | ACOXL | 1:3~1:6 | Negative | Online Inquiry |
ACOXL Gene Knockout Cell Lines are genetically engineered cell lines designed to eliminate the expression of the ACOXL (Acyl-CoA Oxidase-Like) gene. This targeted gene knockout facilitates in-depth studies of gene function, metabolic pathways, and cellular responses to various stimuli, making it a vital tool in modern molecular biology.
The primary mechanism of these knockout cell lines involves the precise disruption of the ACOXL gene through CRISPR-Cas9 technology or similar gene-editing techniques. By knocking out ACOXL, researchers can investigate the biological role of this gene in lipid metabolism, particularly its influence on fatty acid oxidation and energy homeostasis. With these insights, scientists can elucidate the pathological roles of ACOXL in metabolic disorders, including obesity and type 2 diabetes.
The scientific importance of ACOXL Gene Knockout Cell Lines extends beyond basic research; they are pivotal in translational studies aimed at the development of new therapeutic strategies. By providing a robust model for evaluating the effects of potential drugs on altered metabolic pathways, these cell lines have applications in drug discovery and precision medicine.
Compared to conventional methods of gene silencing, such as RNA interference, the knockout approach yields stable and heritable changes in gene expression. This stability allows for long-term studies and consistent experimental conditions. Moreover, ACOXL knockout models can be generated in various cell types, including primary human cells, enhancing their applicability across different research contexts.
For researchers and clinicians, the value of ACOXL Gene Knockout Cell Lines lies in their ability to provide a clearer understanding of gene function and its broader implications in health and disease. These innovative tools empower users to conduct more reliable experiments and develop targeted interventions.
Our company specializes in cutting-edge genetic engineering technologies and is committed to advancing scientific research with high-quality products such as the ACOXL Gene Knockout Cell Lines. We pride ourselves on enhancing research with precision, reliability, and scientific excellence.
Please note that all services are for research use only. Not intended for any clinical use.
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