Gene: ACD
Official Full Name: ACD shelterin complex subunit and telomerase recruitment factorprovided by HGNC
Gene Summary: This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20292 | ACD Knockout cell line (HeLa) | Human | ACD | 1:3~1:6 | Negative | Online Inquiry |
KO20293 | ACD Knockout cell line (HCT 116) | Human | ACD | 1:2~1:4 | Negative | Online Inquiry |
KO20294 | ACD Knockout cell line (HEK293) | Human | ACD | 1:3~1:6 | Negative | Online Inquiry |
KO20295 | ACD Knockout cell line (A549) | Human | ACD | 1:3~1:4 | Negative | Online Inquiry |
ACD Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, designed to facilitate the study of gene function and associated biological pathways. These cell lines are engineered to possess a specific gene knockout, achieved through advanced techniques such as CRISPR-Cas9. This targeted gene disruption allows researchers to observe the resultant phenotypic changes and infer the gene's role within cellular processes, ultimately providing insights into various biological functions, disease mechanisms, and potential therapeutic targets.
The primary mechanism of ACD Gene Knockout Cell Lines involves the precise deletion of target genes, which can lead to varied biological outcomes such as altered cell proliferation, changes in metabolic pathways, or modified drug sensitivity. This specificity permits detailed functional studies, enabling researchers to dissect complex genetic networks with high accuracy. The utility of these cell lines extends to both basic research, facilitating fundamental insights into gene expression and regulation, as well as applied research in drug development and genetic disease modeling.
One of the key advantages of ACD Gene Knockout Cell Lines is their ready-to-use nature, which significantly reduces the time and resources typically required for de novo cell line generation. As compared to traditional knockdown methods, such as RNA interference, knockout strategies provide a more robust and permanent alteration of gene function, thereby offering clearer insights into gene function. Furthermore, our cell lines are designed with high transfection efficiency and stability, ensuring consistency and reproducibility in experimental outcomes.
For researchers and clinicians, ACD Gene Knockout Cell Lines present immense value by streamlining experimental workflows and enhancing the reliability of results. The ability to explore gene function in a controlled environment accelerates discoveries in fields such as oncology, neurology, and regenerative medicine, paving the way for novel therapeutic interventions.
ACD’s expertise in the realm of genetic tools is firmly rooted in our commitment to innovation and quality. With a diverse portfolio of biological products and an unwavering focus on facilitating advanced research, we stand as a trusted partner in your scientific journey.
Please note that all services are for research use only. Not intended for any clinical use.
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