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ABHD1 Knockout Cell Lines

Gene: ABHD1

Official Full Name: abhydrolase domain containing 1provided by HGNC

Gene Summary: This gene is a member of the AB hydrolase superfamily and encodes a protein with an alpha/beta hydrolase fold. This domain is common to a number of hydrolytic enzymes of widely differing phylogenetic origins and catalytic functions. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24711 ABHD1 Knockout cell line (A549) Human ABHD1 1:3~1:4 Negative Online Inquiry

Background

ABHD1 Gene Knockout Cell Lines are specialized cellular models designed for in-depth studies of the Abhydrolase Domain Containing 1 (ABHD1) gene, a critical enzyme implicated in lipid metabolism and signaling pathways. These cell lines are engineered to lack functional copies of the ABHD1 gene, allowing researchers to investigate the gene's role in cellular processes such as endocannabinoid signaling, inflammation, and metabolic regulation.

The key mechanism of action revolves around the disruption of the ABHD1 gene, which affects the hydrolysis of fatty acid amides and endocannabinoids. This modification enables scientists to delineate the biological functions of ABHD1, providing insights into various physiological and pathological states. By employing these knockout cell lines, researchers can assess the impact of ABHD1 deficiency on metabolic fluxes, cellular signaling pathways, and responses to pharmacological agents.

The scientific importance of ABHD1 Gene Knockout Cell Lines lies in their versatility for both basic and applied research. In clinical settings, they can aid in elucidating the mechanisms underlying metabolic disorders, neurodegenerative diseases, and the pharmacodynamics of cannabinoid-based therapies. This makes them a valuable tool in drug discovery and the development of therapeutic strategies targeting metabolic pathways.

Compared to traditional cell lines, ABHD1 Gene Knockout Cell Lines provide a novel approach to understanding gene function in a more physiological context. Their unique selling points include precise gene editing, enhanced reproducibility, and a robust platform for high-throughput screening applications, positioning them as superior alternatives for research on lipid signaling and related fields.

Investing in these cell lines not only enhances the value of research projects but also accelerates the transition of findings from the bench to clinical usage. By leveraging our extensive expertise in cellular biology and genetic engineering, our company delivers cutting-edge biological products that empower researchers and clinicians to push the boundaries of scientific inquiry and therapeutic innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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