NEIL3 Knockout cell line (NCM460)

Catalog Number: KOA70478

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Specifications

Product Information
Product Name	NEIL3 Knockout cell line (NCM460)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adheren
Passage ratio	1:2~1:3
species	Human
Gene	NEIL3
Gene ID	55247
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	NCM460
Quality Control	Genotype: NEIL3 Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	nei like DNA glycosylase 3provided by HGNC
Also known as	FGP2; FPG2; NEI3; ZGRF3; hFPG2; hNEI3
Gene Description	NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]
Expression	Biased expression in bone marrow (RPKM 2.5), lymph node (RPKM 1.9) and 13 other tissues See more

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