CCR7 Knockout cell line (BEAS-2B)

Name: CCR7 Knockout cell line (BEAS-2B)
Brand: CD Biosynsis
SKU: KOA31953
Availability: InStock

Catalog Number: KOA31953

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Specifications

Product Information
Product Name	CCR7 Knockout cell line (BEAS-2B)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:4
species	Human
Gene	CCR7
Gene ID	1236
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10% FBS
Parental Cell Line	BEAS-2B
Quality Control	Genotype: CCR7 Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	C-C motif chemokine receptor 7provided by HGNC
Also known as	BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7
Gene Description	The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Expression	Biased expression in lymph node (RPKM 35.2), appendix (RPKM 32.5) and 6 other tissues See more

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