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PCK1 Knockout cell line (BEAS-2B)

Catalog Number: KOA29865

Price: Online Inquiry

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Specifications

Product Information
Product Name PCK1 Knockout cell line (BEAS-2B)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adherent
Passage ratio 1:3~1:4
species Human
Gene PCK1
Gene ID 5105
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90% DMEM+10% FBS
Parental Cell Line BEAS-2B
Quality Control Genotype: PCK1 Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name phosphoenolpyruvate carboxykinase 1provided by HGNC
Also known as PCKDC; PEPCK1; PEPCKC; PEPCK-C
Gene Description This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008]
Expression Biased expression in liver (RPKM 471.7), kidney (RPKM 448.1) and 4 other tissues See more

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