Gene: TMPPE
Official Full Name: transmembrane protein with metallophosphoesterase domainprovided by HGNC
Gene Summary: Predicted to enable hydrolase activity and metal ion binding activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13159 | TMPPE Knockout cell line (HCT 116) | Human | TMPPE | 1:2~1:4 | Negative | Online Inquiry |
KO13160 | TMPPE Knockout cell line (HEK293) | Human | TMPPE | 1:3~1:6 | Negative | Online Inquiry |
KO13161 | TMPPE Knockout cell line (A549) | Human | TMPPE | 1:3~1:4 | Negative | Online Inquiry |
TMPPE Gene Knockout Cell Lines are specialized biological tools designed to facilitate the study of gene function and regulation in various cellular contexts. These cell lines have been engineered through precise genetic editing techniques to eliminate the expression of the TMPPE gene, allowing researchers to investigate the biological consequences of its absence. By providing a predictable and reproducible model, TMPPE gene knockout cell lines serve as vital resources in understanding gene interactions and cellular pathways essential for biological processes.
The primary function of these targeted knockout cell lines is to enable the exploration of gene function through loss-of-function studies. By observing the phenotypic changes arising from the absence of TMPPE, researchers can elucidate its role in critical biological mechanisms such as cell proliferation, apoptosis, and signal transduction. These knockout models rely on advanced CRISPR-Cas9 genome-editing technology, which ensures high specificity and efficiency in creating precise mutations, thereby enhancing the reliability of experimental outcomes.
The scientific importance of TMPPE gene knockout cell lines is underscored by their extensive applications in both research and clinical settings. They are invaluable in drug discovery, genetic disease modeling, and understanding the molecular underpinnings of diseases where TMPPE is implicated. Moreover, the insights gained from these models can inform therapeutic strategies, potentially leading to novel interventions for diseases linked to dysfunctional TMPPE signaling pathways.
Compared to traditional methods of gene silencing, such as RNA interference, TMPPE knockout cell lines offer superior specificity in gene editing. Unlike transient knockdown approaches, these stable lines provide consistent expression profiles over time, minimizing variability and enhancing the robustness of experimental data. Their user-friendly design allows for seamless integration into diverse experimental workflows, making them an excellent choice for both seasoned researchers and those new to genetic manipulation.
For researchers and clinicians alike, TMPPE Gene Knockout Cell Lines represent a significant advancement in the toolkit available for functional genomics. Their ability to provide clear insights into the role of TMPPE in cellular physiology makes them invaluable for advancing knowledge in molecular biology and therapeutic development. With years of expertise in biomolecular research, our company is committed to delivering high-quality biological products that support science and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.