Gene: TAF1A
Official Full Name: TATA-box binding protein associated factor, RNA polymerase I subunit Aprovided by HGNC
Gene Summary: This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33655 | TAF1A Knockout cell line (HeLa) | Human | TAF1A | 1:3~1:6 | Negative | Online Inquiry |
KO33656 | TAF1A Knockout cell line (HCT 116) | Human | TAF1A | 1:2~1:4 | Negative | Online Inquiry |
KO33657 | TAF1A Knockout cell line (HEK293) | Human | TAF1A | 1:3~1:6 | Negative | Online Inquiry |
KO33658 | TAF1A Knockout cell line (A549) | Human | TAF1A | 1:3~1:4 | Negative | Online Inquiry |
TAF1A Gene Knockout Cell Lines are advanced biological research tools designed to facilitate the study of the TAF1A gene, which encodes a subunit of the transcription factor TFIID essential for RNA polymerase II-mediated transcription. The knockout allows for the complete removal of TAF1A gene expression, thereby enabling researchers to investigate the gene’s role in cellular processes such as gene regulation, cell growth, and differentiation. By utilizing CRISPR-Cas9 technology, these cell lines ensure precise gene disruption, providing a reliable model to study gene function and the resulting phenotypic alterations.
The key function of TAF1A Gene Knockout Cell Lines lies in their ability to mimic gene loss conditions, thus allowing scientists to assess the downstream effects on various biological pathways. This is particularly valuable for understanding the mechanisms underlying diseases where TAF1A may play a crucial role, such as certain cancers or neurodegenerative disorders. These cell lines offer a unique advantage in providing a pure, controlled environment to dissect the complex interactions within cellular systems, making them indispensable for both basic and translational research.
Compared to traditional methods of gene silencing, such as RNA interference, TAF1A Gene Knockout Cell Lines provide a more stable and permanent solution for gene knockout, minimizing off-target effects and prolonging viability for prolonged studies. This makes them an optimal choice for researchers seeking robust and reproducible experimental models.
For researchers and clinicians, these cell lines are immensely valuable as they can lead to the discovery of novel therapeutic targets and the development of innovative strategies in gene therapy. The ability to understand the broader implications of TAF1A in cellular physiology can significantly impact the future of medical research and treatment.
Our company specializes in providing high-quality biological products, and our TAF1A Gene Knockout Cell Lines exemplify our commitment to advancing scientific discovery through innovative solutions. Leveraging cutting-edge technology and a deep understanding of molecular biology, we strive to empower the research community with tools that drive forward the boundaries of science.
Please note that all services are for research use only. Not intended for any clinical use.
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