Gene: SYTL1
Official Full Name: synaptotagmin like 1provided by HGNC
Gene Summary: Predicted to enable neurexin family protein binding activity. Involved in exocytosis. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24407 | SYTL1 Knockout cell line (HCT 116) | Human | SYTL1 | 1:2~1:4 | Negative | Online Inquiry |
KO24408 | SYTL1 Knockout cell line (HEK293) | Human | SYTL1 | 1:3~1:6 | Negative | Online Inquiry |
SYTL1 Gene Knockout Cell Lines are genetically engineered cell lines in which the SYTL1 gene has been deliberately disrupted or "knocked out" to facilitate comprehensive studies of the gene's function and associated biological pathways. SYTL1 encodes a member of the synaptotagmin-like protein family, which plays a crucial role in intracellular trafficking and membrane dynamics. By utilizing these knockout cell lines, researchers can investigate the phenotypic consequences of SYTL1 disruption, elucidating its involvement in processes such as vesicular transport, cellular signaling, and potential implications in various diseases.
The primary mechanism of action underpinning the SYTL1 Gene Knockout Cell Lines is the targeted disruption of the SYTL1 gene through CRISPR-Cas9 or similar gene-editing methodologies. This results in a loss-of-function phenotype, enabling the assessment of cellular behavior, morphology, and signaling pathways in the absence of SYTL1. The resulting insights are invaluable for understanding the gene's role in cellular homeostasis, trafficking processes, and its correlation with pathological conditions, such as neurodegenerative diseases, where dysregulation of intracellular transport mechanisms is often observed.
Scientifically, these knockout cell lines serve an essential dual purpose in both research and clinical settings. They provide a powerful platform for drug discovery, enabling the identification of novel therapeutic targets, and facilitate the investigation into gene function, potentially leading to breakthroughs in our comprehension of conditions associated with SYTL1. By allowing researchers to model loss-of-function phenotypes, these tools add significant depth to functional genomics studies.
Key advantages of the SYTL1 Gene Knockout Cell Lines include their precise gene modification, consistent reproducibility, and ease of use, setting them apart from conventional knockdown strategies that may yield transient effects. Furthermore, as compared to existing alternatives, our cell lines are readily available with well-characterized backgrounds, ensuring that researchers can obtain reliable results.
In summary, SYTL1 Gene Knockout Cell Lines represent an invaluable resource for scientists, offering a unique perspective on gene function that is instrumental for advancing biomedical research. Our company is committed to providing high-quality biological products supported by extensive expertise in genetic engineering and cell line development, ensuring that researchers and clinicians can confidently explore the complexities of gene regulation and its broader implications in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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