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SMYD2 Knockout Cell Lines

Gene: SMYD2

Official Full Name: SET and MYND domain containing 2provided by HGNC

Gene Summary: SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06723 SMYD2 Knockout cell line (HeLa) Human SMYD2 1:3~1:6 Negative Online Inquiry
KO06724 SMYD2 Knockout cell line (HCT 116) Human SMYD2 1:2~1:4 Negative Online Inquiry
KO06725 SMYD2 Knockout cell line (HEK293) Human SMYD2 1:3~1:6 Negative Online Inquiry
KO06726 SMYD2 Knockout cell line (A549) Human SMYD2 1:3~1:4 Negative Online Inquiry

Background

SMYD2 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the expression of the SMYD2 gene, which encodes a protein with critical roles in histone methylation and gene regulation. This innovative product provides a unique tool for researchers examining the intricate mechanisms underlying cellular processes such as proliferation, differentiation, and epigenetic regulation. By knocking out the SMYD2 gene, these cell lines enable the study of resultant phenotypic changes and facilitate the dissection of pathways involved in various diseases, including cancer.

The primary function of the SMYD2 gene is to encode a lysine methyltransferase that modifies histones, thereby influencing chromatin structure and gene transcription. Inhibiting SMYD2 provides insights into its role in oncogenic signaling pathways and tumorigenesis, making these knockout cell lines essential for translational research. The application of these cell lines can be pivotal in drug discovery, where researchers can explore the effects of SMYD2 inhibition or restoration on cellular behavior, contributing to the identification of novel therapeutic targets.

Compared to traditional methods such as transient transfections or RNA interference, our SMYD2 Gene Knockout Cell Lines offer a stable and precise genetic modification that ensures reproducibility and reliability in experimental outcomes. Furthermore, they provide a more efficient means of studying the long-term impact of genetic alterations on cell function, which is often a limitation of other temporary expression systems.

For researchers and clinicians focused on cancer biology, epigenetics, and drug development, these cell lines represent a powerful asset, enhancing the depth of analysis and the potential for impactful discoveries. The commitment to quality and precision in our genetic engineering processes reflects our expertise in the field and our dedication to advancing scientific research. By offering these specialized knockout cell lines, we support the scientific community in uncovering the complexities of gene function and its implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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