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SLC44A3 Knockout Cell Lines

Gene: SLC44A3

Official Full Name: solute carrier family 44 member 3provided by HGNC

Gene Summary: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27114 SLC44A3 Knockout cell line (HCT 116) Human SLC44A3 1:2~1:4 Negative Online Inquiry
KO27115 SLC44A3 Knockout cell line (HEK293) Human SLC44A3 1:3~1:6 Negative Online Inquiry
KO27116 SLC44A3 Knockout cell line (A549) Human SLC44A3 1:3~1:4 Negative Online Inquiry

Background

SLC44A3 Gene Knockout Cell Lines represent a pioneering advancement in cellular biology, focusing on the targeted deletion of the SLC44A3 gene, which encodes for a specific solute carrier protein involved in choline transport. These engineered cell lines serve as a vital tool for researchers looking to investigate the physiological and pathological roles of choline transport in cellular processes, particularly in cancer biology and neurological disorders.

The key function of SLC44A3 knockout cell lines lies in their ability to elucidate the role of choline as a signaling molecule and its impact on cell proliferation, differentiation, and metabolic control. By disrupting the SLC44A3 gene, these cell lines allow for in-depth studies of choline-related metabolic pathways, revealing insights into the molecular mechanisms underlying various diseases. Researchers can manipulate these cell lines for applications such as drug screening, metabolic profiling, and investigating choline-mediated cellular pathways.

The scientific importance of SLC44A3 knockout cell lines extends into both basic and applied research. In clinical settings, they are invaluable for understanding the connections between choline metabolism and conditions like cancer and neurodegeneration, ultimately contributing to the development of targeted therapies. Compared to traditional cell lines, which may express varying levels of SLC44A3, these knockout models provide a consistent and reliable platform for investigating choline dynamics, making them indispensable for precise and reproducible research outcomes.

Additionally, the advantages of SLC44A3 gene knockout cell lines include high specificity, the ability to model disease states accurately, and the potential for high-throughput screening. Researchers and clinicians alike will appreciate the reduction of background noise associated with off-target effects, enabling clearer interpretations of experimental data.

Our company prides itself on its expertise in developing cutting-edge biological products tailored for research and clinical applications. With SLC44A3 Gene Knockout Cell Lines, we empower scientists to unlock the mysteries of cellular metabolism and push the boundaries of therapeutic development, ensuring that your research is supported by robust and innovative tools.

Please note that all services are for research use only. Not intended for any clinical use.

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