Home / SHCBP1 Knockout Cell Lines

SHCBP1 Knockout Cell Lines

Gene: SHCBP1

Official Full Name: SHC binding and spindle associated 1provided by HGNC

Gene Summary: Predicted to enable SH2 domain binding activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway and regulation of neural precursor cell proliferation. Predicted to be located in cytoplasm; midbody; and spindle. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14157 SHCBP1 Knockout cell line (HeLa) Human SHCBP1 1:3~1:6 Negative Online Inquiry
KO14158 SHCBP1 Knockout cell line (HCT 116) Human SHCBP1 1:2~1:4 Negative Online Inquiry
KO14159 SHCBP1 Knockout cell line (HEK293) Human SHCBP1 1:3~1:6 Negative Online Inquiry
KO14160 SHCBP1 Knockout cell line (A549) Human SHCBP1 1:3~1:4 Negative Online Inquiry

Background

SHCBP1 Gene Knockout Cell Lines are engineered cellular models that are designed to elicit the specific disruption of the SHCBP1 gene, a crucial component implicated in various cellular processes, including cytoskeletal dynamics and signal transduction pathways. By employing advanced CRISPR-Cas9 technology, these knockout cell lines allow researchers to effectively study the gene's functions and its role in pathophysiological conditions such as cancer and metabolic disorders.

The primary mechanism involves the targeted introduction of double-strand breaks at the SHCBP1 locus, leading to gene inactivation through non-homologous end joining. This results in a loss-of-function phenotype that can be monitored through various assays examining cell morphology, proliferation, and signaling responses. The ability to manipulate the SHCBP1 gene facilitates a deeper understanding of its contribution to cellular behavior, making it an invaluable tool for research in molecular biology and genetics.

The scientific importance of SHCBP1 Gene Knockout Cell Lines spans several applications in both basic research and clinical settings. They are pivotal for studying gene function and elucidating the molecular mechanisms underlying disease progression. Furthermore, these cell lines may serve as platforms for drug screening and therapeutic development, allowing researchers to assess the efficacy of new treatments targeting SHCBP1-related pathways.

Compared to conventional methods of gene silencing, such as RNA interference or chemical inhibitors, SHCBP1 Gene Knockout Cell Lines provide a stable genetic model that yields more permanent and specific results. This specificity minimizes off-target effects and variability, unlike transient transfection methods, thus providing higher reproducibility in experimental outcomes.

For researchers and clinicians seeking technology that supports rigorous scientific inquiry, the reliability of these knockout cell lines is indispensable. They empower studies that advance our understanding of cellular processes and contribute to the discovery of novel therapeutic avenues.

Our company specializes in providing high-quality biological products and cutting-edge genetic tools tailored to meet the demands of contemporary research. With a commitment to innovation and excellence, we equip scientists with resources that facilitate breakthroughs in genomic and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.