Gene: RGS19
Official Full Name: regulator of G protein signaling 19provided by HGNC
Gene Summary: G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32019 | RGS19 Knockout cell line (HeLa) | Human | RGS19 | 1:3~1:6 | Negative | Online Inquiry |
KO32020 | RGS19 Knockout cell line (HCT 116) | Human | RGS19 | 1:2~1:4 | Negative | Online Inquiry |
KO32021 | RGS19 Knockout cell line (HEK293) | Human | RGS19 | 1:3~1:6 | Negative | Online Inquiry |
KO32022 | RGS19 Knockout cell line (A549) | Human | RGS19 | 1:3~1:4 | Negative | Online Inquiry |
RGS19 Gene Knockout Cell Lines are engineered cellular models designed specifically to elucidate the role of the RGS19 gene in various biological processes. RGS19, or Regulator of G-protein signaling 19, plays a pivotal role in modulating G-protein signaling pathways, which are critical for numerous cellular functions including growth, differentiation, and response to external stimuli. The knockout cell lines effectively eliminate the expression of RGS19, allowing researchers to investigate the gene's functional contributions and the resultant phenotypic changes in a controlled environment.
The main function of these cell lines is to provide a robust platform for studying cellular signaling cascades affected by the absence of RGS19. By creating specific deficiencies, researchers can assess alterations in downstream signaling pathways, cellular proliferation, apoptosis, and migration, thereby gaining insights into potential therapeutic targets for diseases related to dysfunctional G-protein signaling, such as cancer and cardiovascular disorders.
In both research and clinical settings, RGS19 Gene Knockout Cell Lines hold significant scientific value. They empower scientists to probe the intricacies of G-protein signaling with unparalleled accuracy, facilitating the discovery of new pharmacological interventions. Compared to traditional methods, these knockout models provide a precise and reproducible system to dissect the cellular biology associated with RGS19 function, thereby streamlining the drug development process.
One of the standout advantages of RGS19 Gene Knockout Cell Lines is their unparalleled specificity in eliminating RGS19 activity without off-target effects, making them a superior choice over transient knockdown methods that may lead to inconsistent results. Additionally, their versatility allows for a range of downstream applications, from basic research to high-throughput screening for drug discovery.
For researchers and clinicians aiming to understand the critical roles of G-protein signaling in health and disease, investing in RGS19 Gene Knockout Cell Lines is invaluable. Our company boasts extensive expertise in molecular biology and genetic engineering, ensuring that our products meet the highest standards of quality and reliability. Be part of the forefront of biological research with our cutting-edge cellular models tailored for your scientific inquiries.
Please note that all services are for research use only. Not intended for any clinical use.
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