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RETREG3 Knockout Cell Lines

Gene: RETREG3

Official Full Name: reticulophagy regulator family member 3provided by HGNC

Gene Summary: Predicted to enable endoplasmic reticulum-autophagosome adaptor activity. Involved in endoplasmic reticulum tubular network organization; positive regulation of neuron projection development; and reticulophagy. Located in endoplasmic reticulum tubular network. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14604 RETREG3 Knockout cell line (HeLa) Human RETREG3 1:3~1:6 Negative Online Inquiry
KO14605 RETREG3 Knockout cell line (HCT 116) Human RETREG3 1:2~1:4 Negative Online Inquiry
KO14606 RETREG3 Knockout cell line (HEK293) Human RETREG3 1:3~1:6 Negative Online Inquiry
KO14607 RETREG3 Knockout cell line (A549) Human RETREG3 1:3~1:4 Negative Online Inquiry

Background

RETREG3 Gene Knockout Cell Lines are a suite of genetically modified cell lines designed to study the functional roles of the RETREG3 gene, which is implicated in processes such as cell survival, autophagy, and immune response. These knockout cell lines are generated through advanced CRISPR-Cas9 technology, ensuring precise deletions of the RETREG3 gene, which allows researchers to investigate the cellular consequences of its absence in vitro. By eliminating this specific gene, scientists can elucidate its biological functions, cellular pathways, and interactions with other genes, thus providing a clearer picture of its role in disease mechanisms.

The primary function of the RETREG3 Gene Knockout Cell Lines lies in their ability to facilitate targeted studies on autophagy regulation and cellular stress responses. By studying how the absence of RETREG3 affects cellular morphology, proliferation, and apoptosis, researchers can better understand its contributions to various pathophysiological conditions, including cancer and neurodegenerative diseases. The unique mechanism of action associated with RETREG3 also highlights its potential to influence therapeutic strategies that aim to manipulate cellular stress responses.

In terms of scientific importance, these knockout cell lines serve as critical tools for researchers in both academic and clinical settings. They provide an invaluable resource for drug discovery, enabling researchers to identify potential therapeutic targets through loss-of-function analyses. Furthermore, RETREG3 knockout models could be pivotal in exploring immune system dynamics, particularly in the context of autoimmune disorders and infections.

Compared to existing alternatives, such as traditional RNA interference methods, the RETREG3 Gene Knockout Cell Lines offer enhanced specificity and robustness. They allow for permanent gene disruption, providing a more stable platform for long-term studies compared to transient knockdown techniques that may lead to off-target effects or incomplete gene silencing.

For researchers and clinicians, the availability of RETREG3 Gene Knockout Cell Lines is an exceptional asset that accelerates the pace of scientific discovery and contributes to the advancement of personalized medicine. Our company prides itself on its expertise in genetic engineering and cell line development, providing researchers with high-quality, reliable resources that empower them to push the frontiers of biological research. By harnessing our expertise, you can be confident that you are utilizing the best tools available to further your investigations in molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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