Gene: RAB9A
Official Full Name: RAB9A, member RAS oncogene familyprovided by HGNC
Gene Summary: Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in negative regulation by host of symbiont catalytic activity; positive regulation of exocytosis; and regulation of protein localization. Located in late endosome; lysosome; and phagocytic vesicle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33286 | RAB9A Knockout cell line (HeLa) | Human | RAB9A | 1:3~1:6 | Negative | Online Inquiry |
KO33287 | RAB9A Knockout cell line (HCT 116) | Human | RAB9A | 1:2~1:4 | Negative | Online Inquiry |
KO33288 | RAB9A Knockout cell line (HEK293) | Human | RAB9A | 1:3~1:6 | Negative | Online Inquiry |
KO33289 | RAB9A Knockout cell line (A549) | Human | RAB9A | 1:3~1:4 | Negative | Online Inquiry |
RAB9A Gene Knockout Cell Lines are specialized cultured cell lines designed to facilitate the study of the RAB9A gene, which encodes a small GTPase that plays a critical role in intracellular trafficking processes, particularly in vesicle transport between late endosomes and the trans-Golgi network. By creating knockout variants of these cell lines, researchers can effectively assess the functional consequences of RAB9A gene deletion on cellular pathways and protein trafficking mechanisms.
The key function of the RAB9A Gene Knockout Cell Lines lies in their ability to mimic physiological disruptions, enabling the investigation of the gene’s role in various cellular processes such as autophagy, signal transduction, and pathogen defense mechanisms. These cell lines are engineered using CRISPR/Cas9 technology, ensuring precise gene editing and the generation of stable knockout models that exhibit reproducible results in experimental settings.
The scientific importance of utilizing these knockout cell lines cannot be overstated, particularly in research areas focusing on neurodegenerative diseases, cancer biology, and infectious diseases. Understanding the role of RAB9A may unveil novel therapeutic targets and treatment strategies, thereby enhancing clinical outcomes.
Compared to alternative methods like RNA interference, RAB9A Gene Knockout Cell Lines offer permanent gene inactivation, leading to more consistent and long-lasting results. Additionally, these lines allow for the assessment of complex biological functions in a more controlled environment, reducing variability and increasing the reliability of experimental data.
For researchers and clinicians alike, the RAB9A Gene Knockout Cell Lines represent a valuable resource in advancing understanding of intracellular dynamics. With our company’s extensive expertise in genetic engineering and commitment to providing high-quality biological products, we are dedicated to supporting the scientific community in uncovering insights that can lead to breakthroughs in health and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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