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PHAF1 Knockout Cell Lines

Gene: PHAF1

Official Full Name: phagophore assembly factor 1provided by HGNC

Gene Summary: Predicted to be involved in Golgi to plasma membrane protein transport. Located in phagophore assembly site. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15199 PHAF1 Knockout cell line (HeLa) Human PHAF1 1:3~1:6 Negative Online Inquiry
KO15200 PHAF1 Knockout cell line (HCT 116) Human PHAF1 1:2~1:4 Negative Online Inquiry
KO15201 PHAF1 Knockout cell line (HEK293) Human PHAF1 1:3~1:6 Negative Online Inquiry
KO15202 PHAF1 Knockout cell line (A549) Human PHAF1 1:3~1:4 Negative Online Inquiry

Background

PHAF1 Gene Knockout Cell Lines are genetically engineered cell systems designed to facilitate the study of PHAF1 (photoreceptor-specific phosphoesterase and farnesyltransferase 1) gene functions by completely disabling the expression of this target gene. This precise knockout allows researchers to delve into the molecular mechanisms underlying PHAF1-associated biological processes, providing a versatile platform for functional genomics and therapeutic research.

The key mechanism of these cell lines involves CRISPR/Cas9 technology, which employs a guided RNA to target the PHAF1 gene for disruption, leading to a loss of protein function. This enables scientists to investigate phenotypic changes, signaling pathways, and potential compensatory mechanisms within the cell, thereby elucidating the gene’s role in various biological contexts, including cell differentiation, signaling, and pathology.

Scientifically, PHAF1 Gene Knockout Cell Lines are invaluable for research and clinical applications such as cancer biology, neurobiology, and drug response studies, where understanding PHAF1’s role can uncover new therapeutic targets or biomarkers. These cell lines can assist in drug discovery efforts and the development of precision medicine approaches tailored to conditions influenced by PHAF1.

What sets our PHAF1 Gene Knockout Cell Lines apart from alternatives is their rigorous validation, specificity to the PHAF1 gene, and the high-quality controls in place throughout the production process. Additionally, each line is produced with strict adherence to ethical guidelines, ensuring reproducibility and reliability of the data generated.

For researchers and clinicians, the value of our PHAF1 Gene Knockout Cell Lines lies in their ability to significantly advance understanding of gene function with reliable, reproducible results essential for future innovations. By integrating cutting-edge technology and a commitment to scientific excellence, our company is dedicated to supporting the global research community with high-quality biological tools that drive discoveries in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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