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OLA1 Knockout Cell Lines

Gene: OLA1

Official Full Name: Obg like ATPase 1provided by HGNC

Gene Summary: This gene encodes a member of the GTPase protein family. The encoded protein interacts with breast cancer-associated gene 1 (BRCA1) and BRCA1-associated RING domain protein (BARD1), and is involved in centrosome regulation. Overexpression of this gene has been observed in multiple types of cancer and may be associated with poor survival. Pseudogenes of this gene have been defined on chromosomes 17 and 22. [provided by RefSeq, Jun 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00657 OLA1 Knockout cell line (HeLa) Human OLA1 1:3~1:6 Negative Online Inquiry
KO00969 OLA1 Knockout cell line (L-02) Human OLA1 1:2~1:4 Negative Online Inquiry
KO01436 OLA1 Knockout cell line(LoVo) Human OLA1 Negative Online Inquiry
KO01437 OLA1 Knockout cell line(HCT 116) Human OLA1 1:2~1:4 Negative Online Inquiry

Background

OLA1 Gene Knockout Cell Lines are sophisticated cellular models engineered to effectively disrupt the expression of the OLA1 gene, which encodes a protein implicated in various cellular processes including DNA repair, cell cycle regulation, and stress response pathways. These cell lines serve as invaluable tools for elucidating the functional roles of OLA1 in both physiological and pathological contexts, providing insights into molecular mechanisms underlying various diseases, including cancer and neurodegenerative disorders.

The core functionality of OLA1 Gene Knockout Cell Lines lies in their precise genetic modification, achieved through advanced CRISPR-Cas9 technology. This targeted approach ensures complete disruption of the OLA1 gene, allowing researchers to observe the resultant phenotypic changes linked to its absence. By utilizing these knockout cell lines, scientists can rigorously investigate the gene’s contribution to critical biological processes, assess drug responses, and evaluate cellular behaviors such as proliferation, apoptosis, and migration.

The scientific importance of these cell lines is underscored by their broad applicability in both research and clinical settings. They can be used in drug discovery to identify potential therapeutic targets and in varying experimental setups to simulate disease conditions. Furthermore, OLA1 Knockout Cell Lines are vital for generating preclinical models that can lead to novel treatment strategies, making them indispensable for advancing therapeutic development.

What sets OLA1 Gene Knockout Cell Lines apart from other genetic models is not only their high specificity but also their robust reproducibility and ease of use. Researchers benefit from a consistent and reliable platform that allows for varying experimental designs while ensuring significant data integrity.

For researchers, clinicians, and biotechnology companies, OLA1 Gene Knockout Cell Lines represent a powerful and versatile resource for advancing biological understanding and developing innovative therapies. The unparalleled expertise and cutting-edge technology of our company in genetic editing and cell line development ensures that you receive high-quality products designed to meet rigorous scientific standards, ultimately enhancing your research capabilities and clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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