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NES Knockout Cell Lines

Gene: NES

Official Full Name: nestinprovided by HGNC

Gene Summary: This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02466 NES Knockout cell line (HeLa) Human NES 1:3~1:6 Negative Online Inquiry
KO02467 NES Knockout cell line (HCT 116) Human NES 1:2~1:4 Negative Online Inquiry
KO02468 NES Knockout cell line (HEK293) Human NES 1:3~1:6 Negative Online Inquiry
KO02469 NES Knockout cell line (A549) Human NES 1:3~1:4 Negative Online Inquiry

Background

NES Gene Knockout Cell Lines are specifically engineered cellular models that have undergone targeted gene deletion for the neurodevelopmental gene Nestin (NES). These cell lines provide a powerful tool for studying the roles and mechanisms of Nestin in cellular processes, signaling pathways, and overall developmental biology. By utilizing CRISPR-Cas9 technology, researchers can precisely eliminate the NES gene, allowing for the investigation of its contributions in various biological contexts, such as neuronal differentiation, stem cell behavior, and repair mechanisms in neurogenesis.

The primary function of NES Gene Knockout Cell Lines lies in their ability to simulate loss-of-function scenarios, giving researchers insights into the physiological and pathological implications of Nestin. With a deeper understanding of how Nestin influences neural stem cell proliferation and differentiation, these cell lines serve as a critical resource in neurobiology research. They pave the way for uncovering potential therapeutic targets for neurodegenerative diseases and developing novel strategies for regenerative medicine.

What sets NES Gene Knockout Cell Lines apart from traditional cell models is their unparalleled specificity and accuracy in targeting the Nestin gene. Unlike other methods that may result in partial or non-specific mutations, our knockout cell lines ensure complete gene ablation, significantly enhancing the reproducibility and reliability of experimental outcomes.

These cell lines are invaluable to researchers and clinicians alike; they open avenues for pioneering studies in brain injury, repair, and tumor biology. Their high-quality, customizable nature facilitates a variety of experimental designs, from basic research to therapeutic applications, making them indispensable tools for any laboratory focused on neurological health.

As a company with a profound commitment to advancing biological research, we dedicate significant resources to the development of cutting-edge products that equip scientists with the best tools necessary for innovation. Trust in our expertise to enhance your research capabilities and drive meaningful discoveries in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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