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LRRC7 Knockout Cell Lines

Gene: LRRC7

Official Full Name: leucine rich repeat containing 7provided by HGNC

Gene Summary: Predicted to enable protein kinase binding activity. Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; protein localization to postsynapse; and receptor clustering. Located in several cellular components, including centrosome; cytosol; and nucleoplasm. Implicated in cocaine dependence. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16474 LRRC7 Knockout cell line (HEK293) Human LRRC7 1:3~1:6 Negative Online Inquiry

Background

LRRC7 Gene Knockout Cell Lines are innovative biological tools engineered to facilitate the study of the Leucine-Rich Repeat Containing protein 7 (LRRC7), a key player in synaptic organization and function. These cell lines have been meticulously designed using CRISPR/Cas9 technology to ablate the LRRC7 gene, allowing researchers to explore the physiological and pathological roles of LRRC7 in neuronal signaling and synaptic architecture.

The primary function of LRRC7 is its involvement in anchoring proteins to the postsynaptic density, thereby influencing synaptic strength and plasticity. The knockout of this gene enables an unprecedented opportunity to examine the changes in synaptic morphology and activity, providing critical insights into neurodevelopmental disorders and neurodegenerative diseases. This makes the LRRC7 Gene Knockout Cell Lines a valuable resource for neuroscience research, allowing scientists to model conditions such as Alzheimer's Disease or autism spectrum disorders.

Compared to traditional methods of gene knockdown, such as RNA interference, the LRRC7 Gene Knockout Cell Lines offer permanent and complete gene disruption, which can yield more robust phenotypic changes and facilitate the study of compensatory mechanisms caused by the absence of LRRC7. Additionally, these cell lines are derived from widely used cellular platforms, ensuring ease of compatibility with existing experimental protocols.

Researchers and clinicians can greatly benefit from accessing these cell lines, as they provide a reliable means to elucidate the molecular pathways that underlie synaptic dysfunction. By utilizing the LRRC7 Gene Knockout Cell Lines, users can gain deeper insights into drug targets and therapeutic strategies, thus advancing the field of neurobiology.

Our company specializes in providing high-quality biological products that empower researchers to push the boundaries of scientific discovery. With an emphasis on precision and reliability, we are committed to supporting the scientific community with cutting-edge tools that foster innovation in cellular and molecular research.

Please note that all services are for research use only. Not intended for any clinical use.

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