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LRCH4 Knockout Cell Lines

Gene: LRCH4

Official Full Name: leucine rich repeats and calponin homology domain containing 4provided by HGNC

Gene Summary: This gene encodes a protein that contains leucine-rich repeats (LRR) at its amino terminus and that is known to be involved in ligand binding. The carboxyl terminus may act as a membrane anchor. Identified structural elements suggest that the encoded protein resembles a receptor. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36784 LRCH4 Knockout cell line (HeLa) Human LRCH4 1:3~1:6 Negative Online Inquiry
KO36785 LRCH4 Knockout cell line (HCT 116) Human LRCH4 1:2~1:4 Negative Online Inquiry
KO36786 LRCH4 Knockout cell line (HEK293) Human LRCH4 1:3~1:6 Negative Online Inquiry
KO36787 LRCH4 Knockout cell line (A549) Human LRCH4 1:3~1:4 Negative Online Inquiry

Background

LRCH4 Gene Knockout Cell Lines are specialized cellular models developed to facilitate the study of LRCH4 gene function and its role in various biological processes. These cell lines are engineered using cutting-edge CRISPR/Cas9 gene-editing technology to specifically disrupt the LRCH4 gene within the cellular genome, leading to a complete knockout of its expression. This strategic manipulation allows researchers to investigate the consequences of LRCH4 loss on cell behavior, signaling pathways, and phenotypic traits, thus providing significant insights into its potential involvement in disease mechanisms.

The key function of LRCH4 Gene Knockout Cell Lines is to serve as an experimental platform for elucidating the protein's biological role. By enabling the assessment of cellular responses to the absence of the LRCH4 protein, researchers can explore its impact on critical cellular processes such as apoptosis, proliferation, and differentiation. Mechanistically, the cell lines elucidate the pathways affected by LRCH4, allowing for a comprehensive understanding of how dysregulation may contribute to pathological conditions, such as cancer or immune disorders.

The scientific importance of these knockout cell lines extends to numerous applications in both research and clinical settings. They are invaluable tools for gene expression studies, drug screening, and the development of novel therapeutic strategies aimed at modulating LRCH4-related pathways. Their use could accelerate the identification of biomarkers and therapeutic targets relevant to diseases wherein LRCH4 plays a pivotal role.

What sets LRCH4 Gene Knockout Cell Lines apart from traditional cell lines and other genetic models is their precise genomic editing, which offers greater specificity and efficiency. Other methods may introduce off-target effects that can confound experimental results; however, the CRISPR-based approach ensures higher fidelity in genetic disruption. Additionally, these cell lines are developed under stringent quality controls, ensuring reproducibility and reliability in experimental outcomes.

Researchers and clinicians will find tremendous value in utilizing LRCH4 Gene Knockout Cell Lines, as they provide a robust platform for advancing understanding of LRCH4's role in health and disease, thus paving the way for innovative research that could translate into effective therapies. Our company leverages years of experience in cellular biology and genetic engineering to deliver top-of-the-line biological products, supporting the scientific community with reliable and state-of-the-art research tools.

Please note that all services are for research use only. Not intended for any clinical use.

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