Gene: KLHDC2
Official Full Name: kelch domain containing 2provided by HGNC
Gene Summary: Enables ubiquitin-like ligase-substrate adaptor activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in nuclear body and nuclear membrane. Is active in Cul2-RING ubiquitin ligase complex and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00261 | KLHDC2 Knockout cell line (293T) | Human | KLHDC2 | 1:3~1:6 | Negative | Online Inquiry |
KO29110 | KLHDC2 Knockout cell line (HeLa) | Human | KLHDC2 | 1:3~1:6 | Negative | Online Inquiry |
KO29111 | KLHDC2 Knockout cell line (HCT 116) | Human | KLHDC2 | 1:2~1:4 | Negative | Online Inquiry |
KO29112 | KLHDC2 Knockout cell line (HEK293) | Human | KLHDC2 | 1:3~1:6 | Negative | Online Inquiry |
KO29113 | KLHDC2 Knockout cell line (A549) | Human | KLHDC2 | 1:3~1:4 | Negative | Online Inquiry |
KLHDC2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the KLHDC2 gene, which plays a crucial role in various cellular processes, including protein degradation and response to environmental stressors. Developed through advanced CRISPR-Cas9 technology, these knockout cell lines provide a powerful tool for researchers and clinicians to study the functional implications of KLHDC2 loss in different biological contexts.
The primary function of KLHDC2 involves the regulation of cellular homeostasis and the modulation of signaling pathways, making its knockout particularly useful for investigating disease mechanisms associated with cellular stress responses. By using these knockout cell lines, researchers can examine the role of KLHDC2 in processes such as apoptosis, cell cycle regulation, and immune response, offering insights that could pave the way for novel therapeutic strategies, especially in cancer and autoimmune diseases.
The scientific importance of KLHDC2 Gene Knockout Cell Lines spans various fields, including molecular biology, genetics, and pharmacology. They serve as invaluable models for understanding the underlying biology of diseases and assessing the efficacy of potential treatments under conditions mimicking human physiological responses.
Compared to traditional knockout methods, our KLHDC2 Gene Knockout Cell Lines provide superior specificity and efficiency due to the precision of CRISPR-Cas9 technology, significantly reducing off-target effects. Furthermore, these specialized cell lines come with a guarantee of high reproducibility and consistency, which are critical for obtaining reliable experimental results.
For researchers, clinicians, and biotechnologists, the KLHDC2 Gene Knockout Cell Lines offer a unique opportunity to delve deep into the challenges posed by KLHDC2-related pathways, ultimately driving innovation in therapeutic development. Our company prides itself on its expertise in genetic engineering and cell line development, ensuring that our products not only meet but exceed the expectations of the scientific community. By choosing our KLHDC2 Gene Knockout Cell Lines, users are assured of high-quality, experimentally validated tools that will enhance their research capabilities.
Please note that all services are for research use only. Not intended for any clinical use.
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