Gene: HSF2BP
Official Full Name: heat shock transcription factor 2 binding proteinprovided by HGNC
Gene Summary: HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31234 | HSF2BP Knockout cell line (HeLa) | Human | HSF2BP | 1:3~1:6 | Negative | Online Inquiry |
KO31235 | HSF2BP Knockout cell line (HEK293) | Human | HSF2BP | 1:3~1:6 | Negative | Online Inquiry |
KO31236 | HSF2BP Knockout cell line (A549) | Human | HSF2BP | 1:3~1:4 | Negative | Online Inquiry |
HSF2BP Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the in-depth study of the HSF2BP gene, which plays a crucial role in cellular stress responses and protein homeostasis. This product is generated through advanced CRISPR-Cas9 technology, ensuring precise and efficient knockout of the gene, enabling researchers to investigate the functional consequences of HSF2BP absence in various biological processes.
The key function of HSF2BP gene knockout cell lines lies in their ability to elucidate the mechanisms by which HSF2BP influences heat shock factor regulation and response to thermal stress. By disrupting the expression of this gene, researchers can explore downstream signaling pathways involved in cell proliferation, differentiation, and apoptosis under stress conditions. This understanding contributes to a broader comprehension of cellular homeostasis, potentially informing therapeutic strategies for stress-related diseases.
In scientific research and clinical settings, these knockout cell lines serve as valuable tools for drug discovery, screening, and the validation of novel therapeutic targets. They empower researchers to model human disease states more accurately, particularly those linked to protein misfolding and neurodegeneration, thus providing insights that are directly translatable to clinical applications.
One of the distinct advantages of HSF2BP Gene Knockout Cell Lines is the specificity and reliability they offer in gene function studies, compared to traditional knockout methods that may yield off-target effects. Furthermore, the ease of use and compatibility with various assays make these cell lines an attractive option for high-throughput screening and functional assays.
Researchers and clinicians seeking to expand their understanding of the cellular mechanisms in stress responses will find immense value in this product. The precision of the knockout approach ensures high-quality data generation, leading to novel insights and potential breakthroughs in therapeutic development. Our commitment to excellence in gene-editing technologies and our extensive experience in cell line production position our company as a leader in providing innovative solutions to the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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