Gene: HSDL1
Official Full Name: hydroxysteroid dehydrogenase like 1provided by HGNC
Gene Summary: Located in intermediate filament cytoskeleton and mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25407 | HSDL1 Knockout cell line (HeLa) | Human | HSDL1 | 1:3~1:6 | Negative | Online Inquiry |
KO25408 | HSDL1 Knockout cell line (HCT 116) | Human | HSDL1 | 1:2~1:4 | Negative | Online Inquiry |
KO25409 | HSDL1 Knockout cell line (HEK293) | Human | HSDL1 | 1:3~1:6 | Negative | Online Inquiry |
KO25410 | HSDL1 Knockout cell line (A549) | Human | HSDL1 | 1:3~1:4 | Negative | Online Inquiry |
HSDL1 Gene Knockout Cell Lines are specialized cellular models that have been engineered to lack the expression of the HSDL1 (hydroxysteroid dehydrogenase-like 1) gene. These cell lines provide researchers with a powerful tool to study the functional implications of HSDL1 deletion, specifically in metabolic pathways and cellular processes where this enzyme is involved. The knockout mechanism typically employs CRISPR-Cas9 or similar genome editing technologies to achieve precise mutations, ensuring the absence of HSDL1 activity and allowing for the examination of downstream effects on cellular metabolism and signaling.
The significance of HSDL1 extends to various physiological contexts, including its role in fatty acid metabolism and steroidogenesis. By utilizing HSDL1 knockout cell lines, scientists can elucidate the contributions of HSDL1 to metabolic disorders, hormone regulation, and even cancer biology. This is particularly valuable in research investigating the biochemical pathways influencing energy homeostasis and the pathophysiology associated with dysregulated metabolism.
One of the primary advantages of HSDL1 Gene Knockout Cell Lines is their specificity and reliability. Unlike alternative models, these knockout lines provide a consistent background for studying the HSDL1-related effects without confounding genetic variables. Additionally, they facilitate high-throughput screening applications, enabling the identification of novel therapeutic targets or biomarkers associated with HSDL1 activity.
Researchers and clinicians can derive significant value from HSDL1 Gene Knockout Cell Lines, as they enable detailed mechanistic studies that can lead to insights into disease mechanisms and potential treatment strategies. With our expertise in molecular biology and commitment to providing high-quality biological products, our company is dedicated to supporting the scientific community in advancing knowledge and improving health outcomes through innovative research tools.
Please note that all services are for research use only. Not intended for any clinical use.
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