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GMEB2 Knockout Cell Lines

Gene: GMEB2

Official Full Name: glucocorticoid modulatory element binding protein 2provided by HGNC

Gene Summary: This gene is a member of KDWK gene family. The product of this gene associates with GMEB1 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation by the glucocorticoid receptor bound to glucocorticoid response elements. This gene appears to use multiple polyadenylation sites. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28226 GMEB2 Knockout cell line (HeLa) Human GMEB2 1:3~1:6 Negative Online Inquiry
KO28227 GMEB2 Knockout cell line (HCT 116) Human GMEB2 1:2~1:4 Negative Online Inquiry
KO28228 GMEB2 Knockout cell line (HEK293) Human GMEB2 1:3~1:6 Negative Online Inquiry
KO28229 GMEB2 Knockout cell line (A549) Human GMEB2 1:3~1:4 Negative Online Inquiry

Background

GMEB2 Gene Knockout Cell Lines are advanced cellular models designed to facilitate the study of gene function by specifically disrupting the GMEB2 gene. These knockout cell lines utilize CRISPR/Cas9 technology, a revolutionary gene-editing tool, to create precise deletions within the GMEB2 locus, resulting in a complete loss of gene expression. This is crucial for researchers aiming to investigate the role of GMEB2 in various biological processes, including cellular stress responses, differentiation, and proliferation.

The functionality of these cell lines stems from their ability to model specific genetic alterations, allowing researchers to observe phenotypic changes and unravel the pathways influenced by GMEB2. By providing a controlled environment where the GMEB2 gene is non-functional, these cell lines enable detailed investigations into its roles in diseases, such as cancer and neurodegenerative disorders, where dysregulation may occur.

The scientific importance of GMEB2 Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical settings. They offer valuable insights into gene interactions, therapeutic targets, and biomarkers for disease progression. Researchers can utilize these models for drug screening and genetic studies, making them indispensable in the fields of molecular biology and pharmacology.

Compared to conventional methods of gene silencing, such as RNA interference (RNAi), GMEB2 gene knockout cell lines provide a more stable and permanent modification, delivering more robust results that can withstand the variability often seen with transient knockdown techniques. This specificity and stability greatly enhance experimental reliability, positioning these cell lines as a superior choice for those engaging in rigorous scientific explorations.

For researchers and clinicians committed to advancing their understanding of GMEB2 and its implications in health and disease, the GMEB2 Gene Knockout Cell Lines represent an invaluable tool. With a focus on high-quality products, our company brings extensive expertise in genetic engineering and cell line development, ensuring that customers receive not only innovative solutions but also comprehensive support in their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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