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FUT10 Knockout Cell Lines

Gene: FUT10

Official Full Name: fucosyltransferase 10provided by HGNC

Gene Summary: Enables fucosyltransferase activity. Involved in N-glycan fucosylation. Located in Golgi apparatus; endoplasmic reticulum; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24655 FUT10 Knockout cell line (HeLa) Human FUT10 1:3~1:6 Negative Online Inquiry
KO24656 FUT10 Knockout cell line (HCT 116) Human FUT10 1:2~1:4 Negative Online Inquiry
KO24657 FUT10 Knockout cell line (HEK293) Human FUT10 1:3~1:6 Negative Online Inquiry
KO24658 FUT10 Knockout cell line (A549) Human FUT10 1:3~1:4 Negative Online Inquiry

Background

FUT10 Gene Knockout Cell Lines are engineered cellular models that have been genetically modified to disrupt the function of the FUT10 gene, which encodes a glycosyltransferase enzyme that plays a critical role in the biosynthesis of certain glycan structures on glycoproteins and glycolipids. By knocking out the FUT10 gene, these cell lines allow researchers to study the resultant phenotypic changes, offering insights into the role of glycosylation in cellular processes such as adhesion, signaling, and immune response.

The primary function of FUT10 Gene Knockout Cell Lines lies in their ability to facilitate investigations into the biological significance of specific glycan modifications. The absence of FUT10 results in a distinctive glycosylation profile, which can be analyzed through advanced techniques such as mass spectrometry and flow cytometry. This adaptability makes them invaluable tools for dissecting the molecular basis of various diseases, including cancer and autoimmune disorders, where aberrant glycosylation is often implicated.

In research and clinical settings, these cell lines are pivotal for the development of glycan-targeted therapeutics and biomarker discovery. By understanding how the FUT10 gene contributes to glycan biosynthesis, scientists can develop strategies to manipulate glycosylation pathways for therapeutic benefit or enhance diagnostic accuracy.

Compared to alternative models, FUT10 Gene Knockout Cell Lines provide a specific and targeted approach to glycosylation research. They offer a more precise tool for investigating the functional consequences of glycan alterations than traditional models, which often exhibit varying degrees of background glycosylation patterns that can confound results.

Our FUT10 Gene Knockout Cell Lines empower researchers and clinicians to deepen their understanding of glycosylation biology, paving the way for innovative solutions and enhanced therapeutic strategies. With our extensive expertise in genetic engineering and commitment to providing high-quality biological reagents, we are dedicated to supporting your scientific endeavors with exceptional products that meet your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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