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FOXD3 Knockout Cell Lines

Gene: FOXD3

Official Full Name: forkhead box D3provided by HGNC

Gene Summary: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. Mutations in this gene cause autoimmune susceptibility 1. [provided by RefSeq, Nov 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06711 FOXD3 Knockout cell line (HEK293) Human FOXD3 1:3~1:6 Negative Online Inquiry

Background

FOXD3 Gene Knockout Cell Lines are specialized cellular models engineered to lack the FOXD3 gene, which plays a crucial role in embryonic development, stem cell pluripotency, and neural crest formation. By utilizing CRISPR-Cas9 technology or similar gene editing methodologies, these cell lines facilitate in-depth investigations into the functions of FOXD3 in various biological contexts, including differentiation pathways and oncogenic processes.

The primary function of FOXD3 is to regulate gene expression involved in maintaining stem cell characteristics and pluripotency. Its knockout results in altered cell behavior, which serves as a valuable tool for researchers to elucidate mechanisms underlying cell lineage commitment and developmental biology. These cell lines can be employed in various applications, ranging from studying stem cell differentiation to modeling diseases associated with aberrant FOXD3 functions, such as certain cancers and neurodevelopmental disorders.

The significance of FOXD3 Gene Knockout Cell Lines extends into both basic research and clinical applications, providing scientists with robust models to investigate the gene's roles in cell signaling and interaction. This can lead to crucial insights into targeted therapies and regenerative medicine strategies. Compared to conventional methods of gene silencing, such as RNA interference, gene knockout provides a more permanent alteration which is essential for long-term studies and functional assays.

Researchers and clinicians will find significant value in these cell lines due to their scalability, reproducibility, and the comprehensive dataset they can generate regarding FOXD3's biological implications. Our commitment to delivering precise and reliable genetic models positions us as a leader in the field of biological research, offering products that not only enhance experimental outcomes but also contribute to groundbreaking advancements in understanding cellular mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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