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FABP7 Knockout Cell Lines

Gene: FABP7

Official Full Name: fatty acid binding protein 7provided by HGNC

Gene Summary: The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37927 FABP7 Knockout cell line (HeLa) Human FABP7 1:3~1:6 Negative Online Inquiry

Background

FABP7 Gene Knockout Cell Lines are strategically engineered cellular models that facilitate the exploration of the functions of the fatty acid-binding protein 7 (FABP7) gene. These knockout cell lines have been derived through precise genome-editing techniques, such as CRISPR-Cas9, which effectively disable the expression of the FABP7 gene, allowing researchers to investigate the phenotypic and molecular effects of its loss.

The primary function of FABP7 is to transport fatty acids and other hydrophobic ligands within cells, impacting energy metabolism, cell signaling, and growth. By utilizing the FABP7 knockout cell lines, scientists can delve into the role of FABP7 in processes such as neuronal development, lipid homeostasis, and various diseases, including cancer and neurodegenerative disorders. The absence of FABP7 facilitates a clearer understanding of its contribution to these biological pathways, providing insights that are critical for potential therapeutic developments.

In research and clinical applications, these knockout cell lines are invaluable tools for validating drug targets and elucidating disease mechanisms attributable to altered fatty acid metabolism. Furthermore, they serve as models for screening compounds that may restore normal functions in cells lacking FABP7, thus identifying novel therapeutic agents.

The unique advantage of our FABP7 Gene Knockout Cell Lines lies in their specificity and reproducibility. Unlike alternative models that may exhibit off-target effects or retain partial gene function, our lines provide a complete loss-of-function scenario, ensuring that results are directly attributable to FABP7 absence. Researchers benefit from these reliable models as they strive to achieve robust data that can enhance translational pathways to clinical applications.

Our commitment to innovative cell line development is backed by a team of experienced geneticists and biologists dedicated to advancing scientific research. By choosing our FABP7 Gene Knockout Cell Lines, you leverage cutting-edge technology to unlock new avenues in biological research and therapeutic discovery, making significant contributions to the field.

Please note that all services are for research use only. Not intended for any clinical use.

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