Gene: ERI2
Official Full Name: ERI1 exoribonuclease family member 2provided by HGNC
Gene Summary: Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to be involved in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30946 | ERI2 Knockout cell line (HeLa) | Human | ERI2 | 1:3~1:6 | Negative | Online Inquiry |
KO30947 | ERI2 Knockout cell line (HCT 116) | Human | ERI2 | 1:2~1:4 | Negative | Online Inquiry |
KO30948 | ERI2 Knockout cell line (HEK293) | Human | ERI2 | 1:3~1:6 | Negative | Online Inquiry |
KO30949 | ERI2 Knockout cell line (A549) | Human | ERI2 | 1:3~1:4 | Negative | Online Inquiry |
ERI2 Gene Knockout Cell Lines are specialized cellular models that have been engineered to lack the expression of the ERI2 gene, which is known to play a critical role in RNA processing and cellular stress responses. These cell lines provide essential tools for researchers investigating gene function, cellular pathways, and disease mechanisms related to ERI2 activity. Utilizing advanced CRISPR-Cas9 technology, our knockout cell lines enable precise gene editing, thus ensuring a reliable platform for experimental validation.
The primary function of ERI2 Gene Knockout Cell Lines is to elucidate the biological roles of ERI2 by allowing researchers to study the consequences of its absence in various cellular contexts. By eliminating this gene, researchers can explore alterations in RNA metabolism, stress response pathways, and their potential implications in diseases such as cancer and neurodegeneration. This makes the ERI2 knockout models invaluable for both basic biological research and translational applications.
In clinical and research settings, these cell lines are crucial for drug development, biomarkers discovery, and understanding therapeutic targets. Unlike traditional cell lines that may express residual ERI2, our knockout model ensures a complete loss of function, thereby providing clear insights into the gene’s role and downstream effects. This specificity offers a significant advantage over other gene manipulation methods that may not completely eliminate gene function.
The uniqueness of our ERI2 Gene Knockout Cell Lines lies not only in their high fidelity and performance but also in the extensive validation that accompanies them, ensuring researchers can confidently attribute observed phenotypes to ERI2 knockdown. This reliability, coupled with robust support for experimental design and troubleshooting, makes these cell lines an attractive option for scientists focused on molecular biology, genetics, and pharmacology.
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Please note that all services are for research use only. Not intended for any clinical use.
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