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CRACDL Knockout Cell Lines

Gene: CRACDL

Official Full Name: CRACD likeprovided by HGNC

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18549 CRACDL Knockout cell line (HeLa) Human CRACDL 1:3~1:6 Negative Online Inquiry
KO18550 CRACDL Knockout cell line (HCT 116) Human CRACDL 1:2~1:4 Negative Online Inquiry
KO18551 CRACDL Knockout cell line (HEK293) Human CRACDL 1:3~1:6 Negative Online Inquiry
KO18552 CRACDL Knockout cell line (A549) Human CRACDL 1:3~1:4 Negative Online Inquiry

Background

CRACDL Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the functional analysis of the Calcium Release Activated Channel Protein 1 (CRACDL), a vital component involved in cellular calcium homeostasis and signaling pathways. These cell lines are created using advanced CRISPR-Cas9 gene-editing technology, which allows for the precise knockout of the CRACDL gene, enabling researchers to study the implications of its absence on cellular physiology and pathology.

The key function of CRACDL Gene Knockout Cell Lines lies in their ability to provide insight into the role of CRAC proteins in various biological processes, such as immune response, muscle contraction, and neuronal signaling. By knocking out the CRACDL gene, researchers can observe alterations in calcium influx and its downstream effects, allowing for the dissection of cellular mechanisms at play in various diseases, including autoimmune disorders and cancer. This model is crucial for elucidating the complexities of calcium signaling and developing potential therapeutic strategies.

In research and clinical settings, the CRACDL Gene Knockout Cell Lines serve as valuable tools for drug discovery, biomarker identification, and mechanistic studies. They offer a reliable platform for pharmaceutical companies and academic institutions to explore the therapeutic potentials of calcium modulators and assess the efficacy of compounds targeting CRAC channels, thus bridging gaps in human health knowledge.

One of the distinctive advantages of utilizing CRACDL Gene Knockout Cell Lines over traditional models is the specificity and accuracy of the gene editing, which yield reliable and reproducible results. Moreover, these knockout lines simplify the study of the CRAC pathway without the confounding effects of functional redundancy observed in wild-type cell lines.

For researchers aiming to decode the intricate roles of calcium signaling in health and disease, CRACDL Gene Knockout Cell Lines represent an indispensable tool that delivers clarity in experimental outcomes. Our company prides itself on its commitment to providing high-quality biological products backed by extensive scientific expertise and a robust understanding of cellular biology, ensuring that users have access to tools that significantly enhance their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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