Gene: CDNF
Official Full Name: cerebral dopamine neurotrophic factorprovided by HGNC
Gene Summary: Predicted to enable growth factor activity. Predicted to be involved in dopaminergic neuron differentiation and neuron projection development. Predicted to be located in extracellular region. Predicted to be active in endoplasmic reticulum and extracellular space. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18861 | CDNF Knockout cell line (HEK293) | Human | CDNF | 1:3~1:6 | Negative | Online Inquiry |
KO18862 | CDNF Knockout cell line (A549) | Human | CDNF | 1:3~1:4 | Negative | Online Inquiry |
CDNF Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the expression of the Cerebral Dopamine Neurotrophic Factor (CDNF) gene. This innovative biological tool offers researchers a critical model to explore the functions of CDNF in cellular processes, particularly those related to neuronal health and neurodegenerative diseases. By knocking out the CDNF gene, scientists are able to elucidate the role of this neurotrophic factor in promoting neuron survival, differentiating neuronal pathways, and mediating responses to cellular stress.
These cell lines operate by producing a significant reduction in CDNF-related signaling pathways, allowing researchers to investigate the effects of CDNF absence on cellular viability, apoptosis, and neurogenesis. The mechanisms underlying CDNF's neuroprotective effects can be critically assessed, enhancing our understanding of neurodegeneration and paving the way for targeted therapeutic strategies.
The scientific importance of CDNF Gene Knockout Cell Lines lies in their applicability in various research domains, including neurobiology, pharmacology, and regenerative medicine. They serve as a valuable platform for testing potential neuroprotective compounds and elucidating the impact of CDNF on the development of neuronal disorders such as Parkinson’s disease and other forms of dementia.
In comparison to traditional models or other gene knockout strategies, our CDNF Gene Knockout Cell Lines offer researchers precision and reliability in their experimental setups. These lines are fully validated, ensuring consistent performance across experiments, and come with a support network from our team of experts, which further enhances their value.
In summary, our CDNF Gene Knockout Cell Lines represent a significant advancement in research technology, allowing for in-depth investigation into CDNF's role in neurobiology. With years of expertise in genetic engineering and cellular biology, our company is dedicated to delivering high-quality biological products to advance scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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