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ATXN7L2 Knockout Cell Lines

Gene: ATXN7L2

Official Full Name: ataxin 7 like 2provided by HGNC

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27110 ATXN7L2 Knockout cell line (HeLa) Human ATXN7L2 1:3~1:6 Negative Online Inquiry
KO27111 ATXN7L2 Knockout cell line (HCT 116) Human ATXN7L2 1:2~1:4 Negative Online Inquiry
KO27112 ATXN7L2 Knockout cell line (HEK293) Human ATXN7L2 1:3~1:6 Negative Online Inquiry
KO27113 ATXN7L2 Knockout cell line (A549) Human ATXN7L2 1:3~1:4 Negative Online Inquiry

Background

ATXN7L2 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the functions and implications of the ATXN7L2 gene, which is implicated in various neurological disorders, including spinocerebellar ataxia. These cell lines are created through homologous recombination techniques that facilitate the complete knockout of the ATXN7L2 gene, allowing researchers to investigate gene function by comparing them with wild-type cell lines.

The primary mechanism of action in these knockout lines involves the loss of ATXN7L2 expression, enabling the assessment of gene behavior, interaction with proteins, and downstream signaling pathways devoid of ATXN7L2's influence. By understanding these pathways, researchers can uncover potential mechanisms of disease progression associated with ATXN7L2, ultimately leading to targeted therapeutic strategies.

The scientific importance of ATXN7L2 Gene Knockout Cell Lines is profound, as they serve as key tools in both research and clinical settings. They provide insights into the molecular underpinnings of neurodegenerative diseases, thereby facilitating drug discovery and development processes. Additionally, they offer a robust platform for high-throughput screening of novel compounds that could modulate ATXN7L2-related pathways.

Unique to our offering, these cell lines are rigorously validated for specificity and functionality, ensuring that researchers obtain reliable and reproducible results. Unlike alternative models that may possess background expression of the target gene, our knockout cell lines provide a clean slate for experimental analysis, minimizing confounding factors.

For researchers, clinicians, and biotechnologists focused on neurobiology and genetic disorders, ATXN7L2 Gene Knockout Cell Lines represent an invaluable asset to elucidate the role of this gene in pathological conditions and to develop interventions that could alter its course. Our company prides itself on providing high-quality biological products that enhance research capabilities, backed by a commitment to scientific excellence and cutting-edge technologies.

Please note that all services are for research use only. Not intended for any clinical use.

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