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ANKRD12 Knockout Cell Lines

Gene: ANKRD12

Official Full Name: ankyrin repeat domain 12provided by HGNC

Gene Summary: This gene encodes a member of the ankyrin repeats-containing cofactor family. These proteins may inhibit the transcriptional activity of nuclear receptors through the recruitment of histone deacetylases. The encoded protein interacts with p160 coactivators and also represses transcription mediated by the coactivator alteration/deficiency in activation 3 (ADA3). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29595 ANKRD12 Knockout cell line (HeLa) Human ANKRD12 1:3~1:6 Negative Online Inquiry
KO29596 ANKRD12 Knockout cell line (HCT 116) Human ANKRD12 1:2~1:4 Negative Online Inquiry
KO29597 ANKRD12 Knockout cell line (HEK293) Human ANKRD12 1:3~1:6 Negative Online Inquiry
KO29598 ANKRD12 Knockout cell line (A549) Human ANKRD12 1:3~1:4 Negative Online Inquiry

Background

ANKRD12 Gene Knockout Cell Lines are specially engineered cell lines that exhibit a complete deletion of the ANKRD12 gene, a key player in several intracellular signaling pathways. By utilizing the CRISPR-Cas9 gene-editing technology, these cell lines allow researchers to study the function of ANKRD12 in detail, particularly its role in cellular processes such as proliferation, differentiation, and response to stress signals.

The primary function of ANKRD12 involves modulation of gene expression and cytoskeletal dynamics, making it crucial for maintaining cellular homeostasis and physiological responses to various stimuli. With the elimination of this gene in our knockout cell lines, scientists can observe phenotypic changes in cell behavior, explore its potential links to disease states, and better understand its contributions to various biological mechanisms. This ensures a focused examination of gene-specific functions without the interference of ANKRD12 activity.

The scientific importance of ANKRD12 Gene Knockout Cell Lines lies in their potential applications across multiple research domains, including cancer biology, developmental biology, and neurobiology. These cell lines can serve as invaluable tools for investigating the relationship between ANKRD12 and various pathologies, including its potential role as a biomarker or therapeutic target.

What sets our ANKRD12 Gene Knockout Cell Lines apart from existing alternatives is their high specificity and validated functionality, coupled with rigorous quality controls underpinned by our in-house expertise. Unlike conventional knockout models, our lines ensure complete gene ablation with minimal off-target effects, enabling reproducible and interpretable results. Additionally, they come with comprehensive technical support and detailed product documentation, empowering users to optimize experimental conditions effectively.

For researchers and clinicians aiming to deepen their understanding of gene function or explore therapeutic interventions, the ANKRD12 Gene Knockout Cell Lines represent a cutting-edge solution. By integrating our product into their workflow, users gain access to a well-characterized platform that accelerates discovery and enhances experimental robustness. With a commitment to excellence and innovation, our company brings extensive experience in genetic engineering technologies to the forefront of biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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