Gene: ZNF701
Official Full Name: zinc finger protein 701provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12047 | ZNF701 Knockout cell line (HeLa) | Human | ZNF701 | 1:3~1:6 | Negative | Online Inquiry |
KO12048 | ZNF701 Knockout cell line (HCT 116) | Human | ZNF701 | 1:2~1:4 | Negative | Online Inquiry |
KO12049 | ZNF701 Knockout cell line (HEK293) | Human | ZNF701 | 1:3~1:6 | Negative | Online Inquiry |
ZNF701 Gene Knockout Cell Lines are specialized cellular models engineered to deactivate the ZNF701 gene, which encodes for a member of the zinc finger protein family involved in transcriptional regulation and cellular signaling pathways. These knockout cell lines serve as critical tools for elucidating the functional roles of the ZNF701 gene in various biological processes and disease mechanisms.
The primary mechanism underlying these cell lines is the targeted disruption of the ZNF701 gene through CRISPR-Cas9 technology. This method enables precise alterations in the genome, leading to a loss-of-function phenotype that can be comprehensively analyzed. Researchers can study the resulting changes in gene expression patterns, protein interactions, and pathway activations, illuminating the gene's contribution to health and disease.
Scientifically, ZNF701 is implicated in several pathological conditions, including certain cancers and neurological disorders. The availability of these knockout cell lines provides researchers in both academic and clinical settings with a robust platform to investigate the gene's role in disease mechanisms, enabling the development of potential therapeutic strategies. Additionally, these models are invaluable for screening drug responses, validating targets for therapeutic intervention, and maintaining the integrity of experimental reproducibility.
Compared to traditional knockdown approaches, such as RNA interference, ZNF701 Gene Knockout Cell Lines offer a more stable and permanent genetic alteration, ensuring that downstream analyses are not confounded by transient effects. This stability, coupled with specificity in targeting, allows for more accurate interpretations of experimental results.
Researchers and clinicians can derive substantial value from utilizing ZNF701 Gene Knockout Cell Lines, as they represent precise, well-characterized tools that enhance the understanding of genetic influences on cellular behavior and disease. By integrating these models into their workflows, users gain insights that propel innovative research and potential clinical applications.
Our company is committed to advancing biological research through the provision of high-quality, reliable gene knockout models like ZNF701 Cell Lines. With our expertise and dedication to scientific excellence, we ensure our products are tailored to meet the diverse needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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