Gene: ZNF473
Official Full Name: zinc finger protein 473provided by HGNC
Gene Summary: This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28677 | ZNF473 Knockout cell line (HeLa) | Human | ZNF473 | 1:3~1:6 | Negative | Online Inquiry |
KO28678 | ZNF473 Knockout cell line (HCT 116) | Human | ZNF473 | 1:2~1:4 | Negative | Online Inquiry |
KO28679 | ZNF473 Knockout cell line (HEK293) | Human | ZNF473 | 1:3~1:6 | Negative | Online Inquiry |
KO28680 | ZNF473 Knockout cell line (A549) | Human | ZNF473 | 1:3~1:4 | Negative | Online Inquiry |
ZNF473 Gene Knockout Cell Lines are genetically engineered cell lines in which the ZNF473 gene has been selectively inactivated or "knocked out" through precise gene-editing techniques such as CRISPR/Cas9. The ZNF473 gene encodes a zinc finger protein that is implicated in various cellular processes, including transcriptional regulation and chromatin remodeling. By utilizing these knockout cell lines, researchers can effectively analyze the functional role of ZNF473 and its contributions to disease mechanisms, particularly in cancer and neurodegenerative disorders.
The primary function of ZNF473 Gene Knockout Cell Lines hinges on their ability to illuminate the biological pathways that ZNF473 influences. When ZNF473 expression is disrupted, researchers can observe downstream effects on gene expression patterns, cellular morphology, and physiological responses. This provides invaluable insight into the gene's role in health and disease, facilitating the understanding of complex biological processes at the cellular level.
Scientifically, these knockout cell lines serve as powerful tools in both basic research and clinical settings. They are essential for elucidating the molecular underpinnings of diseases and can be utilized for drug discovery, biomarker identification, and the development of therapeutic strategies aimed at ameliorating the effects of ZNF473 dysregulation. By offering a clear model for investigating the consequences of gene loss, scientists can derive vital information that aids in clinical translation.
What sets ZNF473 Gene Knockout Cell Lines apart from alternative products is their high specificity and reliability, achieved through rigorous validation protocols. Compared to traditional methods of gene silencing, such as RNA interference, knockout cell lines provide a more definitive approach to understanding gene function without the confounding effects of partial gene expression.
For researchers, clinicians, and pharmaceutical companies, leveraging these knockout cell lines opens pathways to innovative studies, enabling them to tackle complex hypotheses regarding gene function and disease mechanisms. This contributes to the broader scientific endeavor to understand and combat genetic disorders effectively.
Our company boasts unparalleled expertise in genetic engineering and molecular biology, ensuring that our ZNF473 Gene Knockout Cell Lines are of the highest quality and validated for use in a wide range of applications. By choosing our products, you are equipping your research with the precision tools necessary to advance knowledge and therapies in the genomic landscape.
Please note that all services are for research use only. Not intended for any clinical use.
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