Gene: ZC4H2
Official Full Name: zinc finger C4H2-type containingprovided by HGNC
Gene Summary: This gene encodes a member of the zinc finger domain-containing protein family. This family member has a C-terminal zinc finger domain that is characterized by four cysteine residues and two histidine residues, and it also includes a coiled-coil region. This protein has been detected as an autoantigen in hepatocellular carcinoma patients. This gene has been identified as a potential candidate for X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12454 | ZC4H2 Knockout cell line (HeLa) | Human | ZC4H2 | 1:3~1:6 | Negative | Online Inquiry |
KO12455 | ZC4H2 Knockout cell line (HCT 116) | Human | ZC4H2 | 1:2~1:4 | Negative | Online Inquiry |
KO12456 | ZC4H2 Knockout cell line (HEK293) | Human | ZC4H2 | 1:3~1:6 | Negative | Online Inquiry |
KO12457 | ZC4H2 Knockout cell line (A549) | Human | ZC4H2 | 1:3~1:4 | Negative | Online Inquiry |
ZC4H2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed for the functional interrogation of the ZC4H2 gene. This gene plays a significant role in diverse biological processes and is implicated in several diseases, making its study crucial for understanding cellular mechanisms and disease pathology. The knockout of ZC4H2 enables researchers to elucidate the gene's function, analyze its involvement in cellular signaling pathways, and assess its contribution to disease models.
These cell lines utilize advanced CRISPR-Cas9 gene-editing technology to effectively inactivate the ZC4H2 gene, resulting in a model that simulates loss-of-function scenarios. This method ensures precise and efficient gene targeting, allowing for clear observations of phenotypic changes and molecular interactions that the ZC4H2 protein may mediate. As such, these cell lines are invaluable for both academic and industrial research settings, particularly in drug discovery and developmental biology, where understanding the role of specific genes is essential.
The availability of ZC4H2 Gene Knockout Cell Lines represents a distinct advantage over conventional methods, such as RNA interference or chemical inhibitors, which can produce off-target effects or have variable efficacy. Researchers can rely on these knockout cell lines for reproducible results and rigorous analysis, which is vital for validation in studies that explore the gene’s implications in health and disease.
For researchers and clinicians focused on genetic studies, cancer research, or developmental biology, ZC4H2 Gene Knockout Cell Lines offer unparalleled value and insights. The ease of use and robustness of these cell lines make them a preferred choice for elucidating gene function and mechanism-driven research.
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