Gene: TBC1D7
Official Full Name: TBC1 domain family member 7provided by HGNC
Gene Summary: This gene encodes a member of the TBC-domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1-TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus and downstream LOC100130357. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09115 | TBC1D7 Knockout cell line (HeLa) | Human | TBC1D7 | 1:3~1:6 | Negative | Online Inquiry |
KO09116 | TBC1D7 Knockout cell line (HCT 116) | Human | TBC1D7 | 1:2~1:4 | Negative | Online Inquiry |
KO09117 | TBC1D7 Knockout cell line (HEK293) | Human | TBC1D7 | 1:3~1:6 | Negative | Online Inquiry |
KO09118 | TBC1D7 Knockout cell line (A549) | Human | TBC1D7 | 1:3~1:4 | Negative | Online Inquiry |
TBC1D7 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the TBC1D7 gene, which plays a crucial role in cellular signaling pathways related to nutrient sensing and metabolism. These cell lines are generated through advanced CRISPR-Cas9 gene-editing technology, ensuring precise knockout of the target gene, enabling researchers to study the biological consequences of TBC1D7 depletion. The loss of TBC1D7 function can significantly impact cellular processes, including autophagy, insulin signaling, and cellular stress responses, allowing for in-depth investigation into the gene's role in various metabolic disorders.
The primary function of TBC1D7 is believed to act as a regulator of cellular signaling pathways, and its knockout may reveal insights into disease mechanisms such as obesity, diabetes, and cancer. Researchers can utilize these cell lines to explore how the absence of TBC1D7 modifies cellular behavior, aiding in the development of targeted therapies and novel treatments.
Compared to conventional methods of studying gene function, these knockout cell lines provide a robust, homogeneous platform for experimentation, reducing variability and increasing experimental reproducibility. The precise loss of TBC1D7 allows for the investigation of its specific contributions to metabolic regulation, setting these models apart from other less-targeted approaches.
For researchers and clinicians specializing in metabolic diseases or cancer biology, TBC1D7 Gene Knockout Cell Lines represent a valuable tool for unveiling complex biological interactions and pathways. The ability to study this gene in a controlled environment enables more focused research, advancing both fundamental understanding and translational potential in the field.
With extensive experience in gene editing and cellular model development, our company is committed to providing high-quality biological products. Our state-of-the-art facilities and dedicated research teams ensure that our TBC1D7 Gene Knockout Cell Lines facilitate groundbreaking discoveries in biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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